SKIN SUNSTITUTES, PREPARATION METHODS AND USES THEREOF
First Claim
1. A biocomposite membrane for promoting at least one of wound healing and tissue regeneration, comprising poly(ε
- -caprolactone) and gelatin in a weight ratio between 4;
1 to 20;
1.
2 Assignments
0 Petitions
Accused Products
Abstract
Provided herein are skin substitutes suitable for use in a living subject for purpose of repairing damaged tissues, methods of producing the skin substitutes and their uses. A biocomposite membrane comprising poly(ε-caprolactone) (PCL) and at least one material selected from collagen and gelatin is provided. In one embodiment, the biocomposite is a 2-component membrane of PCL and gelatin. In another embodiment, the biocomposite is a 3-component membrane of PCL, collagen and gelatin. The bio-composite membrane may be used directly in vivo as a wound dressing, or as a support for cell growth on each side of the membrane to produce an in vitro cultivated artificial skin for future in vivo and/or in vitro applications.
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Citations
23 Claims
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1. A biocomposite membrane for promoting at least one of wound healing and tissue regeneration, comprising poly(ε
- -caprolactone) and gelatin in a weight ratio between 4;
1 to 20;
1. - View Dependent Claims (2, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 20, 21, 22, 23)
- -caprolactone) and gelatin in a weight ratio between 4;
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3. (canceled)
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4. (canceled)
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15. (canceled)
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16. (canceled)
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17. (canceled)
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18. (canceled)
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19. (canceled)
Specification