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Overexpression of the Chaperone BIP in a Heterokaryon

  • US 20100062491A1
  • Filed: 01/03/2008
  • Published: 03/11/2010
  • Est. Priority Date: 01/05/2007
  • Status: Abandoned Application
First Claim
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1. A method for increasing the production yield of a secreted antibody or antibody fragment in a filamentous fungal host cell, comprising:

  • recombinant expression of the antibody or antibody fragment and over-expression of a BiP chaperone protein.

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