Overexpression of the Chaperone BIP in a Heterokaryon
First Claim
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1. A method for increasing the production yield of a secreted antibody or antibody fragment in a filamentous fungal host cell, comprising:
- recombinant expression of the antibody or antibody fragment and over-expression of a BiP chaperone protein.
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Abstract
The present invention relates to a method for increasing the production yield of a secreted antibody or antibody fragment in a filamentous fungal host cell, comprising: recombinant expression of the antibody or antibody fragment and over-expressing a BiP chaperone protein.
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12 Claims
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1. A method for increasing the production yield of a secreted antibody or antibody fragment in a filamentous fungal host cell, comprising:
- recombinant expression of the antibody or antibody fragment and over-expression of a BiP chaperone protein.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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