METHOD OF IMPROVING SKILLS WITH A COMPOSITION COMPRISING NON-DIGESTIBLE SACCHARIDE

• US 20100063002A1
• Filed: 03/13/2007
• Published: 03/11/2010
• Est. Priority Date: 03/13/2007
• Status: Abandoned Application

• Current Assignee: nv nutricia
• Original Assignee: nv nutricia
• Inventors: Knol, Jan, Stahl, Bernd
• Application Number:
  US12/531,256
• Publication Number:
  US 20100063002A1
• Time in Patent Office: Days
• US Class Current: 514/54
• CPC Class Codes: A23C 9/203 containing bifidus-active substances, e.g. lactulose; containing oligosaccharides
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A23L 33/17 Amino acids, peptides or proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/3202 Prebiotics, ingredients fermented in the gastrointestinal tract by beneficial microflora
• CPC Class Codes: A23V 2200/322 having an effect on the health of the nervous system or on mental function
• CPC Class Codes: A23V 2250/1862 Arachidonic acid
• CPC Class Codes: A23V 2250/1882 Polyunsaturated fatty acids
• CPC Class Codes: A23V 2250/28 Oligosaccharides
• CPC Class Codes: A61K 31/7016 Disaccharides, e.g. lactose, lactulose lactobionic acid A61K31/7032
• CPC Class Codes: A61K 31/702 Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
• CPC Class Codes: A61P 25/00 Drugs for disorders of the nervous system
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention concerns a therapy aimed at language and/or social skills in infants through administration of components stimulating the development of a healthy intestinal flora.

Claims

1. A method for preventing a decline in or improving one of more of (i) language skills, (ii) communication skills, (iii) social skills and (iv) reading skills in a subject, comprising feeding the subject with a non-digestible saccharide composition, thereby preventing said decline in, or improving, said skills.

2. The method according to claim 1 wherein the non-digestible saccharide is selected from the group consisting of a galactooligosaccharide, a fructooligosaccharide and a fructopolysaccharide.

3. The method according to claim 1 wherein the non-digestible saccharide comprises a galacturonic acid oligosaccharide.

4. The method according to claim 1, wherein the composition is a nutritional composition comprising a lipid component, a protein component and a carbohydrate component, wherein:

(a) the lipid component provides 35 to 50% of the total calories,

(b) the protein component provides 7.5 to 12.5% of the total calories, and

(c) the carbohydrate component provides 40 to 55% of the total calories.

5. The method according to claim 1, wherein the subject is an infant.

6. The method according to claim 5, wherein the infant was born prematurely and/or was delivered by caesarean section.

10. The method according to claim 2, wherein the subject is an infant.

11. The method according to claim 10, wherein the infant was born prematurely and/or was delivered by caesarean section.

12. The method according to claim 3, wherein the subject is an infant.

13. The method according to claim 12, wherein the infant was born prematurely and/or was delivered by caesarean section.

14. The method according to claim 4, wherein the subject is an infant.

15. The method according to claim 14, wherein the infant was born prematurely and/or was delivered by caesarean section.

7. A method for treating or preventing a disease or disorder in a subject, comprising feeding the subject with a non-digestible oligosaccharide composition, wherein the treating or preventing comprises:

(i) preventing autistic spectrum disorder in an infant that results from antibiotic treatment

(ii) treating an infant suffering from autistic spectrum disorder that results from antibiotic treatment, or

(ii) preventing Asperger syndrome or Pervasive Developmental Disorder, Not Otherwise Specified (PPD-NOS).

9. The method according to claim 7, wherein the composition is a nutritional composition comprising a lipid component, a protein component and a carbohydrate component, wherein:

(a) the lipid component provides 35 to 50% of the total calories,

(b) the protein component provides 7.5 to 12.5% of the total calories, and

(c) the carbohydrate component provides 40 to 55% of the total calories, and wherein the composition comprises a non-digestible saccharide selected from the group consisting a galactooligosaccharide, a fructooligosaccharide and a fructopolysaccharide.

8. A method for reducing Clostridium counts in an infant subject, comprising feeding the subject with a non-digestible oligosaccharide composition, wherein the subject is

(i) an infant who was delivered by cesarean section,

(ii) a premature infant,

(iii) an infant suffering from an autistic spectrum disorder, and/or

(iv) an infant who has been subjected to antibiotic treatment,

thereby reducing the Clostridium counts.

16. The method according to claim 8, wherein the composition is a nutritional composition comprising a lipid component, a protein component and a carbohydrate component, wherein:

(a) the lipid component provides 35 to 50% of the total calories,

(b) the protein component provides 7.5 to 12.5% of the total calories, and

(c) the carbohydrate component provides 40 to 55% of the total calories, and wherein the composition comprises a non-digestible saccharide selected from the group consisting a galactooligosaccharide, a fructooligosaccharide and a fructopolysaccharide.