DEVICE FOR THE CONTROLLED RELEASE OF A PREDEFINED QUANTITY OF A SUBSTANCE
First Claim
1. Device (10) for the controlled release of a predefined quantity of at least one substance, the device (10) comprising a matrix arrangement of compartments (20), wherein the release of substance of each compartment is controllable by an active matrix (40) and wherein each compartment is closed by at least one release mechanism (30), the active matrix (40) being provided at least partially on a first substrate layer (41) and the release mechanism (30) being provided on a second substrate layer (31).
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Accused Products
Abstract
Device for the controlled release of a predefined quantity of a substance and method for the production of a device for the controlled release of a predefined quantity of a substance. To realize a controlled delivery of a substance based upon a multiplicity of individual compartments, the reservoirs are formed in plastic substrates that allow the substance delivery device to be flexible and conformal with both internal and external body parts. The fabrication technology for the plastic drug release reservoirs is compatible with active matrix array technology, allowing control of delivery to be based upon active matrix principles. Applications are for controlled external drug delivery (patches), implantable drug delivery and oral drug delivery (electronic pill).
14 Citations
23 Claims
- 1. Device (10) for the controlled release of a predefined quantity of at least one substance, the device (10) comprising a matrix arrangement of compartments (20), wherein the release of substance of each compartment is controllable by an active matrix (40) and wherein each compartment is closed by at least one release mechanism (30), the active matrix (40) being provided at least partially on a first substrate layer (41) and the release mechanism (30) being provided on a second substrate layer (31).
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18. Method for the production of a device (10) for the controlled release of a predefined quantity of at least one substance, comprising the steps of
providing a matrix arrangement of compartments (20), providing an active matrix (40) at least partially on a first substrate layer (41) for controlling the release of substance of each compartment, providing a release mechanism (30) for each compartment on a second substrate layer (31), filling the compartments (20) with the substance, laminating the first substrate layer (41) and/or the second substrate layer (31) to a backing plate (50).
Specification