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Modifying a medicament availability state of a final dosage form

  • US 20100068254A1
  • Filed: 02/05/2009
  • Published: 03/18/2010
  • Est. Priority Date: 09/16/2008
  • Status: Abandoned Application
First Claim
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1. An article of manufacture comprising:

  • at least one final dosage form for administering a medicament to an animal, the final dosage form comprising;

    the medicament; and

    a particle or polymeric material carrying the medicament in a medicament-retention state wherein the medicament is substantially not bioavailable to the animal after administration of the final dosage form and modifiable ex vivo to a medicament-release state by an exposure to a stimulus wherein the medicament is substantially bioavailable to the animal after administration of the final dosage form; and

    an instruction for the exposure of the particle or polymeric material ex vivo to a human-initiated stimulus sufficient to transform the particle or polymeric material to allow a discharge of at least a portion of the therapeutically effective amount of the medicament from the particle or polymeric carrier.

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