BUPROPION HYDROBROMIDE POLYMORPHS
First Claim
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1. Bupropion hydrobromide in crystalline form, characterized by at least one of the following properties:
- PXRD as in FIG. 31,DSC as in FIG. 32,TGA as in FIG. 33,IR as in FIG. 34.
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Abstract
Polymorphous and amorphous forms of bupropion hydrobromide are described.
37 Citations
13 Claims
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1. Bupropion hydrobromide in crystalline form, characterized by at least one of the following properties:
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PXRD as in FIG. 31 ,DSC as in FIG. 32 ,TGA as in FIG. 33 ,IR as in FIG. 34 . - View Dependent Claims (7, 8, 9, 10, 11, 12)
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2. Bupropion hydrobromide in crystalline form, characterized by at least one of the following properties:
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PXRD as in FIG. 35 ,DSC as in FIG. 36 ,TGA as in FIG. 37 ,IR as in FIG. 38 .
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3. Bupropion hydrobromide in crystalline form, characterized by at least one of the following properties:
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PXRD as in FIG. 39 ,DSC as in FIG. 40 ,TGA as in FIG. 41 ,IR as in FIG. 42 .
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4. Bupropion hydrobromide in crystalline form, characterized by at least one of the following properties:
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PXRD as in FIG. 43 ,DSC as in FIG. 44 ,TGA as in FIG. 45 ,IR as in FIG. 46 .
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5. Bupropion hydrobromide in amorphous form, characterized by PXRD as in
FIG. 47 .
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6. Bupropion hydrobromide in amorphous form, characterized by PXRD as in
FIG. 48 .
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13. A composition comprising two or more of the following forms of bupropion hydrobromide:
- (a) a crystalline form having the following properties PXRD as in
FIG. 31 , DSC as inFIG. 32 , TGA as inFIG. 33 , IR as inFIG. 34 ;(b) a crystalline form having the following properties PXRD as in FIG. 35 , DSC as inFIG. 36 , TGA as inFIG. 37 , IR as inFIG. 38 ;(c) a crystalline form having the following properties PXRD as in FIG. 39 , DSC as inFIG. 40 , TGA as inFIG. 41 , IR as inFIG. 42 ;(d) a crystalline form having the following properties PXRD as in FIG. 43 , DSC as inFIG. 44 , TGA as inFIG. 45 , IR as inFIG. 46 ;(e) an amorphous form having the following property PXRD as in FIG. 47 ; and(f) an amorphous form having the following property PXRD as in FIG. 48 .
- (a) a crystalline form having the following properties PXRD as in
Specification