BONE MODEL, BONE FILLER AND PROCESS FOR PRODUCING BONE FILLER

• US 20100069455A1
• Filed: 08/20/2007
• Published: 03/18/2010
• Est. Priority Date: 08/21/2006
• Status: Abandoned Application

• Current Assignee: NEXT 21 K.K, University of Tokyo
• Original Assignee: NEXT 21 K.K, University of Tokyo
• Inventors: Saijo, Hideto, Shimizu, Koutaro, Wasada, Shinya, Tei, Yuchi, Takato, Tsuyoshi, Suzuki, Shigeki
• Application Number:
  US12/438,284
• Publication Number:
  US 20100069455A1
• Time in Patent Office: Days
• US Class Current: 514/406
• CPC Class Codes: A61F 2/2875 Skull or cranium A61F2/2803 and A61F2/3099 take precedence
• CPC Class Codes: A61F 2/30942 for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
• CPC Class Codes: A61F 2/4644 Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material bone material A61F2/28; disintegrating or milling devices B02C
• CPC Class Codes: A61P 31/04 Antibacterial agents

Abstract

A method for producing a bone filler basically comprising: a bone model producing step (step 1) for producing a bone model; a figure forming material filling step (step 2) for filling a figure forming material into a bone defect site of the bone model obtained in the bone model producing step; and a bone filler producing step (step 3) for producing a bone filler which is to be filled in a bone defect site based on the figure forming material filled in the bone defect site of the bone model in the figure forming material filling step.

Claims

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17. A method for producing a bone filler comprising:

a bone model producing step for producing a bone model;

a figure-forming material filling step for filling figure-forming material in a bone defect site of the bone model, the bone model being obtained in the bone model producing step;

a figure-forming material digital information obtaining step for obtaining figure-forming material digital information by photographing the bone model, the bone model wherein the figure-forming material is filled in the figure-forming material filling step;

a bone filler producing step for producing a bone filler based on the figure-forming material digital information, the figure forming material digital information being obtained in the figure-forming material digital information obtaining step.

18. The method for producing a bone filler according to claim 17,

wherein the bone model producing step is a step for producing a bone model by the rapid prototype method.

19. The method for producing a bone filler according to claim 17,

wherein the bone model produced in the bone model producing step has contour lines or grid patterns drawn on the surface thereof.

20. The method for producing a bone filler according to claim 17,

wherein the figure-forming material used in the figure-forming material filling step differs from the bone model in one of the X-ray permeability, the infrared rays permeability, or the ultraviolet ray permeability.

21. The method for producing a bone filler according to claim 17,

wherein the figure-forming material used in the figure-forming material filling step contains titanium oxide of the rutile type of 2 to 5 weight parts per 100 weight parts of the total amount.

22. The method for producing a bone filler according to claim 17,

wherein the bone model produced in the bone model producing step contains gypsum as the main ingredient,

wherein the figure-forming material used in the figure-forming material filling step contains wax more than 90 weight parts per 100 weight parts of the total amount, and

wherein the figure-forming material contains titanium oxide of the rutile type of 2 to 5 weight parts per 100 weight parts of the total amount.

23. The method for producing a bone filler according to claim 17,

wherein the bone filler producing step is a step for producing a bone filler by the rapid prototype method.

24. The method for producing a bone filler according to claim 17,

wherein the bone filler producing step comprises:

a kneading step for kneading ingredient comprising calcium-based material and material comprising binder;

a molding step for obtaining a molded body having a predetermined shape from a kneaded material with an injection molding machine having a mold, the kneaded material being obtained in the kneading step;

a binder removal step for obtaining a degreased body by removing the binder contained in the molded body obtained in the molding step; and

a sintering step for obtaining a sintered body by heating and sintering the degreased body obtained in the binder removal step.

25. The method for producing a bone filler according to claim 17, further comprising a step of penetrating or administering an osteogenesis/chondrogenesis promoter, a joint disease therapeutic agent, a preventive and/or therapeutic agent for bone/cartilage disease, a bone-regenerating agent, a bone resorption-suppressing substance, an angiogenesis promoter, an antibacterial agent, an antibiotics, or an anticancer agent into the bone filler, the bone filler being obtained in the bone filler producing step.

26. A method for producing a bone filler comprising:

a bone model producing step for producing a bone model;

a figure-forming material setting step for setting figure-forming material on the bone model, the bone model being obtained in the bone model producing step; and

a figure-forming material digital information obtaining step for obtaining figure-forming material digital information by photographing the bone model, the bone model whereon the figure-forming material is set in the figure-forming material setting step;

a bone filler producing step for producing a bone filler based on the figure-forming material digital information, the figure forming material digital information being obtained in the figure-forming material digital information obtaining step.

27. The method for producing a bone filler according to claim 26,

wherein the bone model produced in the bone model producing step has contour lines or grid patterns drawn on the surface thereof.

28. The method for producing a bone filler according to claim 26,

wherein the figure-forming material used in the figure-forming material filling step differs from the bone model in one of the X-ray permeability, the infrared ray permeability, or the ultraviolet ray permeability.

29. The method for producing a bone filler according to claim 26,

wherein the bone model is a bone model of a patient having bone defect, a patient suffering from bone deformation, or a patient of cosmetic surgery.

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