NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
First Claim
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1. A naphthalenyloxypropenyl derivative of formula (1) or its pharmaceutically acceptable salt:
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Abstract
The present invention discloses novel naphthalenyloxypropenyl derivatives useful for inhibiting the enzyme activity of histone deacetylase, leading effective suppression of cancer cell proliferation.
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9 Claims
- 1. A naphthalenyloxypropenyl derivative of formula (1) or its pharmaceutically acceptable salt:
- 3. A naphthalenyloxypropenyl derivative of formula (2) or its pharmaceutically acceptable salt:
- 5. A naphthalenyloxypropenyl derivative of formula (3) or its pharmaceutically acceptable salt:
- 7. A naphthalenyloxypropenyl derivative of formula (4) or its pharmaceutically acceptable salt:
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