Intelligent medical device system dynamics for biological network regulation
First Claim
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1. A system for operation of a medical device for therapeutics, comprising:
- a therapeutic module consisting of at least two layers;
an analytical module consisting of a system-on-a-chip (SoC);
a set of compartments for storage of chemicals and biologicals;
a set of electrical interconnects;
a set of microfluidic components, including tubes, valves and gates;
at least one integrated circuit;
wherein the layers of components are connected by the electrical interconnects;
wherein the process is controlled by the integrated circuit;
wherein the analytical module uses the SoC to model solutions to pathology optimization problems and transfers the data to the therapeutic module;
wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers;
wherein the medical device compartments are capable of transforming their configurations;
wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations;
wherein the medical device components on one layer transform their configuration by folding gates down to remove partitions and folding gates up to add partitions to create newly configured compartments;
wherein the medical device flushes fluids from its compartments before the transformation process is initiated;
wherein the medical device places chemicals and biologicals into the newly configured compartments on one layer of the device;
wherein the medical device components are coordinated to release specific chemicals and biologicals from newly configured compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations;
wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers;
wherein the resulting therapeutic combination is transmitted to a cell site in a patient;
wherein the feedback is obtained about the remedy and the analytical module updates the model and sends solution options to the pathology to the therapeutic module;
wherein the therapeutic module reconfigures to solve the pathology and combines a new set of chemicals and biologicals according to the revised model in a chamber on one of its layers; and
wherein the resulting revised therapeutic combination is transmitted to a cell site in a patient until the pathology is solved.
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Abstract
The intelligent medical device (iMD) system coordinates the dynamics of hardware and software components in a self-organizing autonomous system. The iMD system uses advanced modeling and metaheuristics to solve complex optimization problems involving the customization of medical therapies. The system uses evolvable hardware and reprogrammable features to coordinate the diagnostic and therapeutic functions of the iMDs.
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Citations
3 Claims
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1. A system for operation of a medical device for therapeutics, comprising:
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a therapeutic module consisting of at least two layers; an analytical module consisting of a system-on-a-chip (SoC); a set of compartments for storage of chemicals and biologicals; a set of electrical interconnects; a set of microfluidic components, including tubes, valves and gates; at least one integrated circuit; wherein the layers of components are connected by the electrical interconnects; wherein the process is controlled by the integrated circuit; wherein the analytical module uses the SoC to model solutions to pathology optimization problems and transfers the data to the therapeutic module; wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers; wherein the medical device compartments are capable of transforming their configurations; wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations; wherein the medical device components on one layer transform their configuration by folding gates down to remove partitions and folding gates up to add partitions to create newly configured compartments; wherein the medical device flushes fluids from its compartments before the transformation process is initiated; wherein the medical device places chemicals and biologicals into the newly configured compartments on one layer of the device; wherein the medical device components are coordinated to release specific chemicals and biologicals from newly configured compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations; wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers; wherein the resulting therapeutic combination is transmitted to a cell site in a patient; wherein the feedback is obtained about the remedy and the analytical module updates the model and sends solution options to the pathology to the therapeutic module; wherein the therapeutic module reconfigures to solve the pathology and combines a new set of chemicals and biologicals according to the revised model in a chamber on one of its layers; and wherein the resulting revised therapeutic combination is transmitted to a cell site in a patient until the pathology is solved.
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2. A system for operation of a medical device for therapeutics, comprising:
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a therapeutic module consisting of at least two layers; an analytical module consisting of a system-on-a-chip (SoC); a set of compartments for storage of chemicals and biologicals; a set of electrical interconnects; a set of microfluidic components, including tubes, valves and gates; at least one integrated circuit; wherein the layers of components are connected by the electrical interconnects; wherein the analytical module uses the SoC to model solutions to pathology optimization problems; wherein the SoC reconfigures its structure to optimize the modeling of the pathology; wherein the SoC uses hybrid metaheuristics to solve the optimization problems; wherein the SoC transfers data on the solution options from the model to the therapeutic module; wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers; wherein the medical device compartments are capable of transforming their configurations; wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations; wherein the medical device components on one layer transform their configuration by folding gates down to remove partitions and folding gates up to add partitions to create newly configured compartments; wherein the pathology addressed is evolutionary; wherein the SoC of the analytical module and the medical device components continuously transform their structures to satisfy the constraints of solving the evolutionary optimization problem presented by the evolving pathology; wherein the medical device places chemicals and biologicals into the newly configured compartments on one layer of the device; wherein the medical device components are coordinated to release specific chemicals and biologicals from newly configured compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations; wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers; wherein the resulting therapeutic combination is transmitted to a cell site in a patient; wherein the feedback is obtained about the remedy and the analytical module updates the model; wherein the SoC continues to transform its structure to solve the evolving optimization problem; wherein the SoC sends solution options to the pathology to the therapeutic module; wherein the therapeutic module reconfigures it architecture to solve the pathology; wherein the therapeutic module combines a new set of chemicals and biologicals according to the revised model in a chamber on one of its layers; and wherein the resulting revised therapeutic combination is transmitted to a cell site in a patient until the pathology is solved.
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3. A system for medical device therapeutics operation having a plurality of system layers interconnected to one another, comprising:
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A first layer including a single iMD device module; a second layer including a specialized iMD; a third layer including a multifunctional iMD; a fourth layer including multiple devices; a fifth layer including the main device and satellite devices; a sixth layer including a configuration of node-to-node devices; a seventh layer including internal and external devices; an eighth layer including system logic comprising semiconductor hardware; a ninth layer including modeling analysis; a tenth layer including the software system, featuring a multi agent system (MAS); an eleventh layer including hybrid metaheuristics used for solving multi-objective optimization problems (MOOPs); a twelve layer including an autonomic computing system for network regulation; and a thirteenth layer including the regulatory network organization for system plasticity.
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Specification