DEVICE AND METHOD FOR TREATING A PART OF A HUMAN OR ANIMAL BODY IMPLEMENTING TREATMENT DOSE DELIVERY MEANS AND DOSIMETRY CONTROL MEANS

• US 20100069895A1
• Filed: 03/03/2009
• Published: 03/18/2010
• Est. Priority Date: 09/16/2008
• Status: Abandoned Application

• Current Assignee: LSO Medical
• Original Assignee: Osyris Medical
• Inventors: Rochon, Philippe, Wassmer, Benjamin, Lefevre, Liliane, Mordon, Serge, Zemmouri, Jaouad
• Application Number:
  US12/396,990
• Publication Number:
  US 20100069895A1
• Time in Patent Office: Days
• US Class Current: 606/9
• CPC Class Codes: A61B 18/20 using laser
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 18/22 the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
• CPC Class Codes: A61B 2017/00075 Motion
• CPC Class Codes: A61B 2017/00123 and automatic shutdown
• CPC Class Codes: A61B 2018/00404 Blood vessels other than those in or around the heart
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00464 Subcutaneous fat, e.g. liposuction, lipolysis
• CPC Class Codes: A61B 2018/0047 Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
• CPC Class Codes: A61B 2018/00636 Sensing and controlling the application of energy
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/0066 without feedback, i.e. open loop control
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00708 switching the power on or off
• CPC Class Codes: A61B 2018/00732 Frequency
• CPC Class Codes: A61B 2018/00779 Power or energy
• CPC Class Codes: A61B 2018/00904 Automatic detection of target tissue
• CPC Class Codes: A61B 2018/2005 with beam delivery through an interstitially insertable device, e.g. needle
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/397 : electromagnetic other than visible, e.g. microwave
• CPC Class Codes: A61B 34/20 : Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 34/25 : User interfaces for surgical systems

Abstract

Device for treatment of a part of a human or animal body, including:

• • treatment dose delivery means enabling treatment doses to be delivered to the human or animal body,
  • mapping means enabling a zone or a volume of the body to be treated to be mapped and spatially defined in a predefined frame of reference and in a form of mapping data,
  • localisation means enabling the instantaneous position of the treatment dose delivery means outlet to be localised in the form of localisation data in the frame of reference,
  • electronic control means, which, are suitable for recording the mapping data of at least one zone or one volume of the body to be treated, acquired with the help of the mapping means, and which, enable a treatment to be controlled by using, during the course of the treatment, at least the mapping data and the localisation data.

Claims

1. Device for treatment of a part of the human or animal body, said device comprising:

treatment dose delivery means enabling treatment doses to be delivered to a part of the human or animal body,

mapping means enabling a zone or a volume of the human or animal body to be treated to be mapped and spatially defined in a predefined frame of reference (Rt) and in the form of mapping data (P_i),

localisation means enabling the instantaneous position of the treatment dose delivery means outlet to be localised in the form of localisation data (P′

) in the said frame of reference (Rt),

electronic control means, which, on the one hand, are suitable for recording said mapping data (P_i) of at least one zone or one volume of the human or animal body to be treated, acquired with the help of said mapping means, and which, on the other hand, enable a treatment to be controlled by using, during the course of the treatment, at least said mapping data (P_i) and said localisation data (P′

).

2. Device according to claim 1, in which said localisation means are adapted to localise the instantaneous position of the treatment dose delivery means outlet, regardless the dose treatment delivery.

3. Device according to claim 2, in which said electronic control means are informed by a signal if a dose treatment is being delivered or not by the treatment dose delivery means.

4. Device according to claim 1, in which said mapping means include a pointing device enabling to point out, on or in the human or animal body, points of the zone or volume to be treated that correspond to said mapping data (P_i).

5. Device according to claim 4, in which said treatment dose delivery means comprise a treatment instrument and the said pointing means are constituted by the said instrument.

6. Device according to claim 1 in which the electronic control means are suitable for displaying on a screen, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out, and to display on said screen during the course of the treatment a cursor that represents the instantaneous position of the outlet of the treatment dose delivery means, which is localised by the localisation means.

7. Device according to claim 1, in which the electronic control means are suitable for displaying on a screen, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out, and to display during the course of the treatment, from at least said localisation data (P′

), a cartography of the instantaneous positions of the delivered treatment doses.

8. Device according to claim 1, in which the electronic control means are suitable for calculating, during the course of a treatment, for each instantaneous position (P′

) localised by the localisation means, the treatment dose delivered, and if necessary accumulated, during the course of the treatment.

9. Device according to claim 8, in which the control means are suitable for displaying on a screen, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out, and for displaying on said screen, during the course of the treatment, a cartography of the treatment doses by associating each calculated treatment dose to its instantaneous position (P′

) localised by the localisation means.

10. Device according to claim 1, in which the electronic control means are suitable for calculating, during the course of a treatment, at least one treatment set point from at least said mapping data (P_i) and said localisation data (P′

).

11. Device according to claim 10, in which the treatment set point is selected from the following group:

treatment dose, displacement speed of the treatment dose delivery means, regulating parameter of the treatment dose delivery means, power of the treatment dose delivery means.

12. Device according to claim 10, in which the electronic control means are suitable for displaying on a screen the treatment set point that is calculated and the real value of the treatment parameter that is measured during the course of the treatment and corresponds to this treatment set point.

13. Device according to claim 10, in which the electronic control means are suitable for automatically commanding the treatment dose delivery means, in function of said treatment set point, and in such a manner as to automatically regulate during the course of treatment the delivered treatment dose.

14. Device according to claim 1, in which the electronic control means are suitable for commanding the treatment dose delivery means, in function of said mapping data (P_i) and said localisation data (P′

).

15. Device according to claim 1, in which the electronic control means are suitable for automatically detecting, from localisation data (P′

) and mapping data (P_i), whether the instantaneous position (P′

) of the outlet of the treatment dose delivery means that is localised by the localisation means is situated outside or inside the zone or volume that has been mapped out.

16. Device according to claim 15, in which the electronic control means are suitable for automatically commanding the inactivation of the dose delivery means, when they detect that the instantaneous position (P′

) of the outlet of the treatment dose delivery means that is localised by the localisation means is situated outside the zone or volume that has been mapped out.

17. Device according to claim 1, in which the electronic control means are suitable for detecting, during the course of a treatment, an overdose or an underdose for each instantaneous position (P′

) localised by the localisation means, by taking into account at least said mapping data (P_i).

18. Device according to claim 17, in which the electronic control means are suitable for commanding the treatment dose delivery means, so as to automatically inactivate the treatment dose delivery means in the event of a detection of an overdose.

19. Device according to claim 1, in which said treatment dose delivery means comprise a treatment instrument, and the localisation means are suitable for delivering localisation data P′

[(x′

(t), y′

(t), z′

(t)] encoding in the frame of reference (Rt) the instantaneous 3D position of the outlet of the instrument via which the treatment doses are delivered.

20. Device according to claim 1, in which said localisation means include at least one sensor, which is fastened to the instrument.

21. Device according to claim 1, in which said treatment dose delivery means comprise a treatment instrument, in which said localisation means include detection means and electronic computation means, in which the detection means include at least one sensor, which is fastened to the instrument at a different position to the outlet position of the treatment instrument, and are suitable for supplying, to the electronic computation means, data P[x(t), y(t), z(t)] encoding the absolute instantaneous 3D position of said sensor, and the data A[α

(t), β

(t), θ

(t)] encoding the absolute instantaneous 3D angle of inclination of said sensor in a predefined three-dimensional reference point (X, Y, Z), and in which the electronic computation means are suitable for calculating the absolute instantaneous 3D position P′

[x′

(t), y′

(t), z′

(t)] of the outlet of the instrument from said data of the absolute instantaneous 3D position P[x(t), y(t), z(t)] and of the absolute instantaneous 3D angle of inclination A[α

(t), β

(t), θ

(t)] of the sensor, and from the relative position Pc (dx,dy,dz) of the sensor in relation to the outlet of the instrument.

22. Device according to claim 21, in which the detection means include emission means for emitting a magnetic field, and in which the sensor of the detection means is sensitive to the magnetic field produced by said emission means and is suitable for delivering electrical signals, which are characteristic of its instantaneous position and of its absolute instantaneous angle of inclination in said magnetic field.

23. Device according to claim 1, in which the treatment dose delivery means comprise a treatment instrument that is invasive.

24. Device according to claim 20, in which the instrument includes a so-called invasive part, which comprises the outlet of the instrument and which is adapted for introduction into a part of the human or animal body, and in which said sensor is positioned in another non-invasive part of the instrument.

25. Device according to claim 1, in which the treatment dose delivery means comprise a treatment instrument and a source of electromagnetic radiation, and in which the treatment instrument includes an optical fibre, which is connected to said source of electromagnetic radiation, and which enables the electromagnetic radiation produced by said source to be delivered at its distal emission extremity, said distal extremity of the optical fibre corresponding to the outlet of the instrument.

26. Device according to claim 20, in which the treatment instrument comprises a cannula, which is threaded and immobilised on the optical fibre, and in which the sensor is integral with the cannula/optical fibre unit.

27. Device according to claim 1, in which the treatment dose delivery means comprise a source of acoustic energy and a treatment instrument that is suitable for delivering the acoustic energy produced by said source.

28. Device according to claim 1, in which the treatment dose delivery means are adapted for destroying adipose cells in a part of human or animal body.

29. Device according to claim 28, in which the treatment dose delivery means are adapted for a lipolysis treatment.

30. Device according to claim 28, in which the treatment dose delivery means are adapted for an adipocytolysis treatment.

31. Device according to claim 1, in which the treatment dose delivery means are adapted for a sub-cutaneous or intra-cutaneous treatment.

32. Device according to claim 1, in which the treatment dose delivery means are adapted for an endovenous treatment.

33. Device according to claim 1, in which the treatment dose delivery means are adapted for heating the collagen present in the dermis.

34. Device according to claim 33, in which the treatment dose delivery means are adapted to, carry a cosmetic skin remodelling or skin healing treatment through heating the collagen present in the dermis.

59. Use of the device according to claim 1 for a sub-cutaneous or intra-cutaneous treatment.

60. Use of the device according to claim 1 for endovenous therapy.

61. Use of the device according to claim 1 for destroying adipose cells in a part of human or animal body.

62. Use of the device according to claim 1 for a lipolysis treatment.

63. Use of the device according to claim 1 for an adipocytolysis treatment.

64. Use of the device according to claim 1 for heating the collagen present in the dermis.

65. Use of the device according to claim 1 for a cosmetic skin remodelling or skin healing treatment through heating the collagen present in the dermis.

35. Treatment method of a part of a human or animal body by means of treatment dose delivery means comprising an instrument, during which:

mapping data (P_i) is obtained that maps out and define, in a predefined frame of reference (Rt), a zone or a volume of the human or animal body to be treated,

the instantaneous position in said frame of reference (Rt) of the treatment instrument outlet is automatically localised during the course of the treatment in the form of localisation data (P′

),

treatment doses are delivered by means of the instrument by displacing the instrument in relation to the part of the human or animal body to be treated,

the treatment is controlled by using at least said mapping data (P_i) and said localisation data (P′

).

36. Method according to claim 35, during which the localisation of the instantaneous position of the treatment instrument outlet is carried out regardless the treatment dose delivery.

37. Method according to claim 35, during which the stage of acquiring mapping data (P_i) is carried out by pointing out the points of the zone or the volume of the human or animal body to be treated by means of a pointing device.

38. Method according to claim 37, during which the stage of acquiring mapping data (P_i) is carried out by using, by way of a pointing device, the treatment instrument, without delivering the treatment dose.

39. Method according to claim 35, during which a screen displays, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out, and during which said screen displays, from at said localisation data (P′

), a cursor that represent the instantaneous position of the treatment dose delivery means outlet.

40. Method according to claim 35, during which a screen displays, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out, and during which said screen displays, from at least said localisation data (P′

), a cartography of the instantaneous positions of the delivered treatment doses during the course of the treatment.

41. Method according to claim 35, during which for each localised instantaneous position (P′

), during the course of the treatment, the treatment dose delivered and, if necessary, accumulated during the course of the treatment, is calculated.

42. Method according to claim 41, during which, from said mapping data (P_i), the zone or the volume of the human or animal body that has been mapped out is displayed on a screen, and a cartography of the treatment doses is displayed on said screen, during the course of the treatment, by associating each calculated treatment dose to its instantaneous position (P′

).

43. Method according to claim 35, during which at least one treatment set point is calculated from at least said mapping data (P_i) and said localisation data (P′

).

44. Method according to claim 43, in which the treatment set point is selected from following group:

treatment dose, speed of displacement of the instrument, regulating parameter of the treatment dose delivery means, power of the treatment dose delivery means.

45. Method according to claim 43, during which the treatment set point, which is calculated, and the real value of the treatment parameter, which is measured during the course of the treatment and which corresponds to this treatment set point, are displayed on a screen.

46. Method according to claim 43, during which the treatment dose delivery means are automatically commanded, in function of said treatment set point, and in such a manner as to automatically regulate during the course of the treatment the treatment dose delivered.

47. Method according to claim 35, during which the dose delivery means are automatically commanded, in function of said mapping data (P_i) and said localisation data (P′

).

48. Method according to claim 35, during which, from localisation data (P′

) and mapping data (P_i), it is automatically detected whether the instantaneous position (P′

) of the treatment dose is situated outside or inside the zone or volume that has been mapped out.

49. Method according to claim 48, during which the dose delivery means are automatically inactivated when it is detected that the instantaneous position (P′

) of the treatment dose is situated outside the zone or volume that has been mapped out.

50. Method according to claim 35, during which an overdose or an underdose is detected by taking into account at least said mapping data (P_i) and said localisation data (P′

).

51. Method according to claim 50, during which the treatment dose delivery means are commanded in such a manner that the treatment dose delivery means are automatically inactivated in the event of a detection of an overdose.

52. Method according to claim 35, during which the instantaneous 3D position P′

[(x′

(t), y′

(t), z′

(t)] of the outlet of the instrument via which the treatment doses are delivered is localised in said frame of reference (Rt).

53. Method according to claim 35, in which the localisation in said frame of reference (Rt) of the instantaneous position of the instrument outlet is carried out by using at least one sensor, which is fastened to the instrument.

54. Method according to claim 52, during which, in order to automatically localise in said frame of reference (Rt) the instantaneous 3D position P′

[(x′

(t), y′

(t), z′

(t)] of the outlet of the instrument delivering the doses, a magnetic field is generated, this magnetic field is detected by means of a sensor, which is positioned on the instrument at a relative position Pc (dx,dy,dz) known in relation to the outlet of the instrument, and the absolute instantaneous 3D position P[x(t), y(t), z(t)] of said sensor and the absolute 3D instantaneous angle of inclination A[α

(t), β

(t), θ

(t)] of said sensor are measured.

55. Method according to claim 35, during which the part of the human or animal body is locally radiated by electromagnetic radiation, at different positions of the instrument.

56. Method according to claim 35, during which the instrument is at least partially introduced into the human or animal body, the instrument is displaced in the part of the human or animal body to be treated and the part of the human or animal body is locally radiated by electromagnetic radiation, at different positions of the instrument.

57. Method according to claim 35, during which acoustic energy is delivered locally in the part of the human or animal body, at different positions of the instrument.

58. Method according to claim 35, during which the instrument is at least partially introduced into the human or animal body, the instrument is displaced in the part of the human or animal body to be treated, and acoustic energy is delivered locally to the part of the human or animal body, at different points of the instrument.

66. Use of the method according to claim 35 for a sub-cutaneous or intra-cutaneous treatment.

67. Use of the method according to claim 35 for endovenous therapy.

68. Use of the method according to claim 35 for destroying adipose cells in a part of human or animal body.

69. Use of the method according to claim 35 for a lipolysis treatment.

70. Use of the method according to claim 35 for an adipocytolysis treatment.

71. Use of the method according to claim 35 for heating the collagen present in the dermis.

72. Use of the method according to claim 35 for a cosmetic skin remodelling or skin healing treatment through heating the collagen present in the dermis