CARDIAC FUNCTION MANAGEMENT INTEGRATING CARDIAC CONTRACTILITY MODULATION
First Claim
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1. An implantable cardiac function management device comprising:
- a cardiac contractility modulation (CCM) therapy circuit configured to deliver a non-stimulatory electrical energy during a refractory period of the heart;
a physiologic sensor circuit configured to sense a physiologic parameter; and
a controller circuit, coupled to the CCM therapy circuit and the physiologic sensor circuit, the controller circuit configured to adjust a CCM therapy using information about the sensed physiologic parameter.
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Abstract
An implantable cardiac rhythm/function management system integrates cardiac contractility modulation (CCM) and one or more other therapies, such as to preserve device safety, improve efficacy, enhance sensing and detection, or enhance therapy effectiveness and delivery. Examples of the one or more other therapies can include pacing, defibrillation/cardioversion, cardiac resynchronization therapy (CRT), or neurostimulation.
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Citations
20 Claims
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1. An implantable cardiac function management device comprising:
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a cardiac contractility modulation (CCM) therapy circuit configured to deliver a non-stimulatory electrical energy during a refractory period of the heart; a physiologic sensor circuit configured to sense a physiologic parameter; and a controller circuit, coupled to the CCM therapy circuit and the physiologic sensor circuit, the controller circuit configured to adjust a CCM therapy using information about the sensed physiologic parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. An implantable cardiac function management device comprising:
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a cardiac contractility modulation (CCM) therapy circuit configured to deliver a non-stimulatory electrical energy during a refractory period of the heart; a physiologic sensor circuit configured to sense a physiologic parameter; and a controller circuit, coupled to the CCM therapy circuit and the physiologic sensor circuit, the controller circuit configured to adjust a CCM therapy using information about the sensed physiologic parameter; wherein the physiologic sensor circuit is configured to sense an indication of a measure of at least one of a renal or cardiac function; and
wherein the controller circuit is configured to use information about the renal or cardiac function to adjust at least one of CCM energy, CCM delivery timing, CCM delivery location, or CCM electrode configuration;wherein the physiologic sensor circuit includes an electrolyte sensor configured to detect an indication of a measure of at least one of;
potassium, sodium, calcium, chloride, or bicarbonate; and
wherein the controller circuit is configured to use information about the measure of the least one of potassium, sodium, calcium, chloride, or bicarbonate, to adjust at least one of CCM energy, CCM delivery timing, CCM delivery location, or CCM electrode configuration;wherein the physiologic sensor circuit is configured to detect an indication of a measure of at least one of;
blood urea nitrogen, serum creatinine, or glomerular filtration rate; and
wherein the controller circuit is configured to use information about the measure of the at least one of;
blood urea nitrogen, serum creatinine, or glomerular filtration rate, to adjust at least one of CCM energy, CCM delivery timing, CCM delivery location, or CCM electrode configuration;wherein the physiologic sensor circuit is a neural sensor configured to sense a neural signal; and
wherein the controller circuit is configured to use information about the neural signal to adjust at least one of CCM energy, CCM delivery timing, CCM delivery location, or CCM electrode configuration; andcomprising a neural stimulation circuit configured to deliver neural stimulation therapy;
wherein the controller circuit is configured to adjust at least one of the CCM therapy or the neural stimulation therapy using information about the other of the CCM therapy or the neural stimulation therapy; and
wherein the controller circuit is configured to adjust at least one of the CCM therapy or the neural stimulation therapy using information about the sensed physiologic parameter.
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Specification