BIOREACTOR JACKET
First Claim
Patent Images
1. A bioreactor bag for affecting the temperature of media held therein, the bag comprising:
- a flexible inner wall defining an inner volume for holding the media; and
a flexible outer wall surrounding at least a portion of the inner wall, the inner wall and the outer wall together defining an outer volume for holding a temperature control fluid therein, the outer volume being separate from the inner volume.
1 Assignment
0 Petitions
Accused Products
Abstract
A bioreactor system (10) is provided for controlling temperature of bioreactor media during processing. The system (10) includes a flexible bag (102) having an inner wall (104) defining an inner volume (105) for holding the cell culture media and an outer wall (106) surrounding at least a portion of the inner wall (104). Together, the inner wall (104) and the outer wall (106) form a jacket volume (107) which can hold a temperature control fluid.
-
Citations
26 Claims
-
1. A bioreactor bag for affecting the temperature of media held therein, the bag comprising:
-
a flexible inner wall defining an inner volume for holding the media; and a flexible outer wall surrounding at least a portion of the inner wall, the inner wall and the outer wall together defining an outer volume for holding a temperature control fluid therein, the outer volume being separate from the inner volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. A bioreactor system for affecting the temperature of media, the system comprising:
-
a flexible jacket bag configured to hold a temperature control fluid and configured to at least partially surround a bioreactor bag when the bioreactor bag is at least partially filled with media, the jacket bag comprising an inlet port configured to receive the temperature control fluid into the jacket bag from a temperature control mechanism, and an outlet port configured to exhaust the fluid from the jacket bag. - View Dependent Claims (18, 19, 20)
-
-
21. A bioreactor bag comprising:
-
first flexible means for holding media in a sterile environment; and second flexible means for holding a temperature control fluid separate from but adjacent to the media, the second flexible means at least partially surrounding the first flexible means, the second flexible means comprising means for receiving and exhausting the temperature control fluid.
-
-
22. A method of regulating the temperature of media during processing, the method comprising:
-
providing a bioreactor bag comprising a flexible inner wall defining an inner volume for holding the media and a flexible outer wall surrounding at least a portion of the inner wall, the inner wall and the outer wall together defining an outer volume for holding a temperature control fluid therein, the outer volume being separate from the inner volume; and filling the outer volume at least partially with the temperature control fluid. - View Dependent Claims (23)
-
-
24. A method of regulating temperature in a flexible bioreactor bag having a first flexible surface configured to hold media and a second flexible surface surrounding at least a portion of the first surface, the first surface and the second surface defining a cavity therebetween, the method comprising:
-
providing fluid into the cavity formed between the first surface of the bioreactor bag and the second surface of the bioreactor bag through an entrance port; exhausting fluid from the cavity through an exit port; and affecting the temperature of media held by the first flexible surface by the temperature of the fluid provided to the cavity. - View Dependent Claims (25, 26)
-
Specification