METHOD AND APPARATUS FOR DETERMINING A RESPIRATION PARAMETER IN A MEDICAL DEVICE

• US 20100076322A1
• Filed: 10/31/2008
• Published: 03/25/2010
• Est. Priority Date: 09/19/2008
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Shrivastav, Maneesh A., Greenhut, Saul E., Kleckner, Karen J., Erickson, Mark K., Cho, Yong K., Bennett, Tommy D., Sperling, Charles P.
• Granted Patent: US 8,372,013 B2
• Time in Patent Office: Days
• US Class Current: 600/484
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/6846 specially adapted to be brought in contact with an internal body part, i.e. invasive
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371
• CPC Class Codes: A61N 1/37258 Alerting the patient

Abstract

A method of determining a respiration parameter in a medical device in which pressure signals are sensed to generate corresponding sample points, and a breath detection threshold is continuously adjusted in response to the generated sample points to generate a current adjusted breath detection threshold. A current generated sample point is compared to the current adjusted breath detection threshold, and the continuous adjusting of the breath detection threshold is suspended and the breath detection threshold is equal to the most current adjusted breath detection threshold generated prior to the suspending in response to the comparing. A next sample point, generated subsequent to the suspending, is compared to the set breath detection threshold, and the respiration parameter is determined in response to the comparing of a next sample point to the set breath detection threshold.

Claims

1. A method of determining a respiration parameter in a medical device, comprising:

sensing pressure signals to generate corresponding sample points;

continuously adjusting a breath detection threshold in response to the generated sample points to generate a current adjusted breath detection threshold;

comparing a current generated sample point to the current adjusted breath detection threshold;

suspending the continuous adjusting of the breath detection threshold and setting the breath detection threshold equal to the most current adjusted breath detection threshold generated prior to the suspending;

comparing a next sample point, generated subsequent to the suspending, to the set breath detection threshold; and

determining the respiration parameter in response to the comparing of a next sample point to the set breath detection threshold.

2. The method of claim 1, wherein the continuously adjusting a breath detection threshold comprises:

storing a predetermined number of generated sample points;

setting the breath detection threshold equal to one of a minimum amplitude and a maximum amplitude of the current stored sample points; and

updating the stored predetermined number of generated sample points to include a subsequently generated sample point.

3. The method of claim 1, further comprising determining whether both an inspiration detection threshold and an expiration detection threshold are sequentially detected in response to the comparing a next sample point.

4. The method of claim 1, wherein the respiration parameter is a breath count.

5. The method of claim 1, further comprising:

confirming detection of an one of an inspiration and an expiration;

resuming the continuous adjusting of the breath detection threshold;

comparing a current sample point, generated subsequent to the resuming, to the current adjusted breath detection threshold;

suspending the continuous adjusting of the breath detection threshold and setting the breath detection threshold equal to the most current adjusted breath detection threshold generated prior to the suspending;

confirming detection of the other of an inspiration and an expiration; and

incrementing a breath count in response to the confirming detection of the other of an inspiration and an expiration.

6. The method of claim 1, further comprising:

determining a heart rate;

filtering the sensed pressure signals in response to the determined heart rate to generate a heart-rate dependent frequency response; and

deriving a filtered signal in response to the heart rate dependent frequency response, wherein the sample points are generated in response to the derived filtered signal.

7. The method of claim 6, wherein filtering the sensed pressure signals comprises filtering the sensed pressure signals using a first filter having a first frequency response corresponding to the determined heart rate being greater than a heart rate threshold and a second filter having a second frequency response different from the first frequency response, the second frequency response corresponding to the determined heart rate being less than the heart rate threshold.

8. The method of claim 7, wherein the first filter and the second filter are selected one at a time in a sequential manner in response to the determined heart rate and the filtered signal is obtained as a continuous signal comprising sequential outputs of the first filter and the second filter.

9. The method of claim 7, wherein filtering the sensed pressure signals comprises selecting the first filter and the second filter simultaneously for parallel filtering of the pressure signals, and wherein the filtered signal comprises a first signal component corresponding to an output of the first filter and a second signal component corresponding to an output of the second filter.

10. The method of claim 7, wherein the first and second filters each comprise multiple filtering stages, the first filter is a subset of the multiple stages of the second filter, and further comprising decimating the pressure signal following at least one of the multiple stages.

11. A method of determining a respiration parameter in a medical device, comprising:

sensing pressure signals to generate corresponding sample points;

continuously adjusting a breath detection threshold in response to a minimum amplitude of a predetermined number of the generated sample points to generate a first detection threshold;

determining whether a current generated sample point is less than the first inspiration detection threshold;

suspending the continuous adjusting of the breath detection threshold and setting the first respiration detection threshold equal to the most current adjusted breath detection threshold generated prior to the suspending;

determining whether a first predetermined number of next sample points, generated subsequent to the suspending, is less than the first respiration detection threshold;

resuming the continuous adjusting of the breath detection threshold to continuously adjust the breath detection threshold in response to a maximum amplitude of the generated sample points to generate a second respiration detection threshold;

determining whether a current generated sample point is greater than the second respiration detection threshold;

suspending the continuous adjusting of the breath detection threshold and setting the expiration detection threshold equal to the most current adjusted breath detection threshold generated prior to the suspending;

determining whether a second predetermined number of next sample points, generated subsequent to the suspending, is greater than the second respiration detection threshold; and

determining the respiration parameter in response to the predetermined number of next sample points being greater than the second respiration detection threshold.

12. The method of claim 11, wherein the first respiration detection threshold is generated using a first computation scheme and the second respiration detection threshold is generated using a second computation scheme different from the first computation scheme.

13. The method of claim 11, wherein the first predetermined number of next sample points is equal to the second predetermined number of next sample points.

14. The method of claim 11, wherein the respiration parameter is a breath count.

15. The method of claim 11, further comprising:

determining a heart rate;

filtering the sensed pressure signals in response to the determined heart rate to generate a heart-rate dependent frequency response; and

deriving a filtered signal in response to the heart rate dependent frequency response, wherein the sample points are generated in response to the derived filtered signal.

16. The method of claim 15, wherein filtering the sensed pressure signals comprises filtering the sensed pressure signals using a first filter having a first frequency response corresponding to the determined heart rate being greater than a heart rate threshold and a second filter having a second frequency response different from the first frequency response, the second frequency response corresponding to the determined heart rate being less than the heart rate threshold.

17. The method of claim 16, wherein the first filter and the second filter are selected one at a time in a sequential manner in response to the determined heart rate and the filtered signal is obtained as a continuous signal comprising sequential outputs of the first filter and the second filter.

18. The method of claim 16, wherein filtering the sensed pressure signals comprises selecting the first filter and the second filter simultaneously for parallel filtering of the pressure signals, and wherein the filtered signal comprises a first signal component corresponding to an output of the first filter and a second signal component corresponding to an output of the second filter.

19. The method of claim 16, wherein the first and second filters each comprise multiple filtering stages, the first filter is a subset of the multiple stages of the second filter, and further comprising decimating the pressure signal following at least one of the multiple stages.