COMPLETE INTEGRATED SYSTEM FOR CONTINUOUS MONITORING AND ANALYSIS OF MOVEMENT DISORDERS

• US 20100076348A1
• Filed: 09/23/2009
• Published: 03/25/2010
• Est. Priority Date: 09/23/2008
• Status: Abandoned Application

• Current Assignee: APDM, Inc.
• Original Assignee: APDM, Inc.
• Inventors: Riobo Aboy, Pedro Mateo, McNames, James, Greenberg, Andrew
• Application Number:
  US12/565,697
• Publication Number:
  US 20100076348A1
• Time in Patent Office: Days
• US Class Current: 600/595
• CPC Class Codes: A61B 2560/0456 Apparatus provided with a docking unit
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/4082 Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette

Abstract

Disclosed embodiments include a complete integrated system designed to support continuous monitoring and objective analysis of movement disorders. According to one embodiment the integrated system allows for continuous monitoring of movement disorders during normal daily activities in home and other normal daily environments, as well as in the clinic. The integrated system comprises: 1) wearable movement monitoring devices including a plurality of inertial sensors, 2) a docking station with wireless capabilities, 3) a secure web-enabled data server, and 4) statistical signal processing methods, all of which are integrated to enable monitoring and analysis of movement disorders.

Claims

1. An integrated movement monitoring system, comprising:

(a) one or more wearable movement monitoring devices comprising one or more movement sensors for collecting a plurality of movement data; and

(b) at least one secure data server for storing said plurality of movement data, said secure data server implemented in a digital computer with one or more processors.

2. The integrated movement monitoring system of claim 1, whereby said one or more movement sensors comprise one or more inertial sensors.

3. The integrated movement monitoring system of claim 2, whereby said inertial sensors include one or more accelerometers.

4. The integrated movement monitoring system of claim 3, whereby said one or more accelerometers are 3-axis accelerometers.

5. The integrated movement monitoring system of claim 4, whereby said inertial sensors include one or more gyroscopes.

6. The integrated movement monitoring system of claim 5, whereby said one or more movement sensors include one or more magnetometers.

7. The integrated movement monitoring system of claim 6, whereby said one or more wearable movement monitoring devices are wireless devices further comprising:

(a) a power source;

(b) a local storage memory;

(c) a microcontroller, and

(d) a wireless transmitter circuit for wireless transmitting said plurality of movement data to a wireless receiver.

8. The integrated movement monitoring system of claim 7, further comprising one or more docking stations, said docking station comprising:

(a) a power supply for powering said docking station;

(b) one or more charging dockets for re-charging said one or more wearable movement monitoring devices; and

(c) an integrated base station.

9. The integrated movement monitoring system of claim 8, whereby said integrated base station comprises:

(a) a power source;

(b) a wireless receiver circuit; and

(c) a wireless transmitter circuit.

10. The integrated movement monitoring system of claim 9, whereby said integrated based station further comprises a connection to a digital computer.

11. The integrated movement monitoring system of claim 10, whereby said digital computer is a regulatory compliant compliant secure data server.

12. The integrated movement monitoring system of claim 11, whereby said secure data server is a web-enabled clinical data management system especially adapted for (a) storing, (b) sharing, (c) managing, and (d) analyzing movement disorder data.

13. The integrated movement monitoring system of claim 12, whereby said web-enabled clinical data management system comprises:

(a) a secure data storage module;

(b) a secure data sharing and collaboration module;

(c) a secure data management module;

(d) a computational engine module; and

(e) a plurality of graphical user interfaces.

14. The integrated movement monitoring system of claim 13, whereby said computational engine module comprises one or more digital signal processing and statistics methods for analysis and processing of said plurality of movement disorder data and automatically generating a report comprising (a) a plurality of movement impairment indices and (b) a plurality of clinical scores.

15. The integrated movement monitoring system of claim 14, whereby said plurality of movement impairment indices comprise (a) a tremor index, (b) a dyskinesia index, and (c) a bradykinesia index.

16. The integrated movement monitoring system of claim 15, whereby said plurality of movement impairment indices further comprises gait, balance, and overall motor state indices, multiple sclerosis, stroke, and neurological injuries and disorders that lead to impaired movement such as traumatic brain injury.

17. The integrated movement monitoring system of claim 16, whereby said report is a downloadable report including a plurality of results including a plurality of (a) numerical results, (b) summary statistical results, (c) tables, (d) time domain plots, (e) frequency domain plots, and (f) time-frequency plots such as spectrograms.

18. The integrated movement monitoring system of claim 17, whereby said web-enabled clinical data management system includes a clinical trials module.

19. The integrated movement monitoring system of claim 18, whereby said clinical trials module further includes a prospective trials module.

20. The integrated movement monitoring system of claim 19, whereby said clinical trials module further includes an exploratory analysis module and a meta studies module.