POLYMERIC FILMS TO ENHANCE CELL GROWTH
First Claim
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1. A method for creating surface-tailored polymer coating for improved cells proliferation comprising the steps of:
- converting one or more carbonaceous monomers comprising one or more functional groups to a monomer vapor;
contacting the monomer vapor and a substrate; and
igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored polymer coating on the substrate at a thicknesses of between 25 and 300 nm and has a functional group surface density of between 3 and 9%, wherein the surface-tailored polymer coating enhances cell proliferation.
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Abstract
The present invention provides a method for creating surface-tailored polymer coating for improved cells proliferation by converting one or more carbonaceous monomers each comprising one or more functional groups to a monomer vapor; contacting the monomer vapor and a substrate; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored polymer coating on the substrate at a thicknesses of between 25 and 300 nm and has a functional group surface density of between 3 and 9%, wherein the surface-tailored polymer coating enhances cell proliferation.
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Citations
20 Claims
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1. A method for creating surface-tailored polymer coating for improved cells proliferation comprising the steps of:
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converting one or more carbonaceous monomers comprising one or more functional groups to a monomer vapor; contacting the monomer vapor and a substrate; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored polymer coating on the substrate at a thicknesses of between 25 and 300 nm and has a functional group surface density of between 3 and 9%, wherein the surface-tailored polymer coating enhances cell proliferation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method for creating surface-tailored vinyl acetic polymer coating for improved cells proliferation comprising the steps of:
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converting one or more vinylacetic acid monomers comprising one or more —
COOH groups to a monomer vapor;contacting the monomer vapor and a substrate; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored vinyl acetic polymer on the substrate at a thicknesses of between 25 and 300 nm and a —
COOH group surface density of between 3.6 and 9%, wherein the surface-tailored vinylacetic acid polymer enhances cell proliferation.
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12. A surface-tailored polymer coated substrate with improved cells proliferation characteristics comprising:
a substrate have a 25 and 300 nm vapor deposited polymer coating comprising one or more functional groups with a functional group surface density of between 3 and 9%, wherein the 25 and 300 nm vapor deposited polymer coating enhances cell proliferation. - View Dependent Claims (13, 14, 15)
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16. A method improving cell proliferation on a substrate comprising the steps of:
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providing a substrate; contacting the substrate with a monomer vapor comprising one or more monomers having one or more functional groups; and igniting a radio frequency plasma glow discharge to polymerize the monomer vapor to form surface-tailored vinyl acetic polymer on the substrate at a thicknesses of between 25 and 300 nm and a functional group surface density of between 3.6 and 9%, wherein the surface-tailored polymer enhances cell proliferation. - View Dependent Claims (17, 18, 19, 20)
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Specification