PULSE-BASED FEATURE EXTRACTION FOR NEURAL RECORDINGS
First Claim
1. A neural acquisition system, comprisinga neural encoder that receives a neural signal and generates a temporal-based pulse-coded representation of the neural signal;
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Abstract
A neural recording system (100) and method (400) for neural encoding is provided. The system can include an ultra-low power neural encoder (120) for compressing spikes within a neural signal (110) to produce a pulse train (130) and wirelessly transmitting the pulse train to a spike sorter (140). Features of the neural signal can be encoded such that the timing between pulses and the number of pulses conveys features of the spike. The neural encoder can include an Integrate and Fire (IF) neuron 230 that performs spike detection and encodes at least one spike (112) of the neural signal. A leakiness aspect (232) and an adaptive aspect (337) can be included with the IF circuit for combining aspects of spike detection and spike sorting for suppressing noise, keeping power consumption low, and improving signal resolution.
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Citations
38 Claims
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1. A neural acquisition system, comprising
a neural encoder that receives a neural signal and generates a temporal-based pulse-coded representation of the neural signal; - and
a spike sorter communicatively coupled to the neural encoder for receiving the temporal-based pulse coded representation, sorting spikes encoded in the temporal-based pulse coded representation, and identifying neurons generating the spikes, wherein the neural encoder encodes features of the spikes as a timing between pulses and a number of pulses such that the timing and the number of pulses represent features of the spikes that are characteristic of neural signals produced by the neurons. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A neural encoder suitable for use in bandwidth compression of a neural signal, the neural encoder comprising:
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an Integrate and Fire (IF) circuit coupled to an electrode that captures a neural signal, wherein the IF circuit encodes at least one spike of the neural signal and generates a bi-phasic pulse train in accordance with features of the spike, wherein the IF circuit introduces a timing between pulses of the pulse train and a number of pulses for encoding at least one feature of the waveform. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17)
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18. An Integrate and Fire (IF) circuit suitable for use in bandwidth compression of a neural signal, comprising:
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a leaky integrator to integrate a neural signal to produce an integrated signal; a pulse generator to produce a bi-phasic pulse train based on the integrated signal, wherein features of the neural signal are encoded as a timing between pulses of the pulse train and a number of pulses such that the timing between pulses and the number of pulses conveys features of the spike. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25)
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26. The IF circuit of claim 26, wherein the adaptive unit adjusts at least one of a resistance of the resistor, a capacitance of the capacitor, a threshold of the bi-phasic comparator, or a delay of a feedback for bandwidth compression of the pulse train.
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27. A method for neural encoding, comprising:
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integrating a neural signal to produce an integrated signal; generating a pulse if a level of the integrated signal exceeds a threshold, wherein characteristic features of the spikes are encoded as a timing between pulses and a number of pulses such that the timing and number of pulses represents features of the neural signal. - View Dependent Claims (28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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Specification