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Devices and Methods for Target Molecule Characterization

  • US 20100084276A1
  • Filed: 04/07/2008
  • Published: 04/08/2010
  • Est. Priority Date: 04/06/2007
  • Status: Active Grant
First Claim
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1. A molecular recognition device configured to identify at least one portion of a target molecule, the device comprising:

  • a partition having a first side and a second side, and at least one constriction passing between the first and second sides, the constriction being shaped and sized to permit translocation of only a single copy of a target molecule therethrough;

    first and second sensing electrodes associated with the first side of the partition and being separated from one another by a first gap;

    a first affinity element connected to the first electrode; and

    a second affinity element connected to the second electrode;

    wherein;

    when a particular portion of a target molecule translocates through the constriction, an electrical current passes through the first electrode, the first affinity element, said particular portion, the second affinity element, and the second electrode.

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