USE OF DIMETHYL SULFONE (MSM) TO REDUCE HOMOCYSTEINE LEVELS

• US 20100087546A1
• Filed: 09/18/2009
• Published: 04/08/2010
• Est. Priority Date: 04/20/2005
• Status: Abandoned Application

• Current Assignee: Biogenic Innovations, LLC (Balchem Corporation)
• Original Assignee: Biogenic Innovations, LLC (Balchem Corporation)
• Inventors: Appleton, Jeremy E.
• Application Number:
  US12/562,942
• Publication Number:
  US 20100087546A1
• Time in Patent Office: Days
• US Class Current: 514/711
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/10 Sulfides; Sulfoxides; Sulfones
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61P 43/00 Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

A method for reducing elevated levels of homocysteine in a subject comprising the steps of measuring the level of homocysteine in a subject; detecting an elevated level of homocysteine in the subject; and responsive to said step of detecting, administering to said subject a nutritional supplement comprising dimethyl sulfone (MSM).

Claims

1. A method for reducing elevated levels of homocysteine in a subject, the method comprising:

measuring a homocysteine level in a subject;

detecting an elevated level of homocysteine in the subject; and

responsive to said step of detecting, administering dimethyl sulfone to said subject,

wherein said dimethyl sulfone is administered in a daily dosage of dimethyl sulfone,

wherein said daily dosage of dimethyl sulfone is greater than 3 grams, and

wherein said dimethyl sulfone reduces the elevated level of homocysteine in the subject.

2. The method of claim 1, wherein dimethyl sulfone is administered in a daily dosage of dimethyl sulfone of between 6 grams to 10 grams.

3. The method of claim 1, wherein said daily dosage is administered in a single dose.

4. The method of claim 1, wherein said daily dosage is administered orally.

5. The method of claim 1, wherein said daily dosage is administered intravenously.

6. The method of claim 1, wherein said dimethyl sulfone reduces the elevated level of homocysteine in the subject by an amount sufficient to reduce pain in said subject.

7. The method of claim 1, wherein said dimethyl sulfone reduces the elevated level of homocysteine in the subject by an amount sufficient to improve physical function in said subject.

8. The method of claim 1, wherein said dimethyl sulfone reduces the elevated level of homocysteine in the subject by at least 10%.

9. The method of claim 1, wherein said dimethyl sulfone reduces the elevated level of homocysteine in the subject by 25-50%.

10. The method of claim 1, wherein said subject has osteoarthritis, and wherein said dimethyl sulfone.

11. The method of claim 1, further comprising administering a second compound to said subject.

12. The method of claim 11, wherein said second ingredient maintains or reduces the homocysteine level.