HEMODYNAMIC MONITORING DURING AUTOMATED MEASUREMENT OF BLOOD CONSTITUENTS
First Claim
1. An apparatus for hemodynamic monitoring and analyte measurement, comprising:
- a. An arterial catheter, configured to be placed in fluid communication with an artery of a patient;
b. A blood pressure monitoring subsystem mounted with the arterial catheter such that the blood pressure monitoring subsystem can determine the pressure of blood in the artery; and
c. An analyte measuring subsystem mounted with the arterial catheter such that the analyte measuring subsystem can determine the presence, concentration, or both of one or more analytes in blood withdrawn from the artery.
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Abstract
The present invention provides methods and apparatuses that can provide measurement of analytes such as glucose with a variety of sensors in connection with hemodynamic monitoring. Some embodiments of the present invention enable the use of a single arterial access site for automated blood glucose measurement as well as hemodynamic monitoring. Some embodiments of the present invention can reduce or eliminate nuisance hemodynamic alarms. Some embodiments of the present invention can provide hemodynamic monitoring during an automated analyte measurement process. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. Such an apparatus also comprises an analyte sensor, mounted with or integrated into the blood access system such that the analyte sensor measures the analyte in the blood that has been removed from the body by the blood access system.
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Citations
16 Claims
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1. An apparatus for hemodynamic monitoring and analyte measurement, comprising:
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a. An arterial catheter, configured to be placed in fluid communication with an artery of a patient; b. A blood pressure monitoring subsystem mounted with the arterial catheter such that the blood pressure monitoring subsystem can determine the pressure of blood in the artery; and c. An analyte measuring subsystem mounted with the arterial catheter such that the analyte measuring subsystem can determine the presence, concentration, or both of one or more analytes in blood withdrawn from the artery. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An apparatus for hemodynamic monitoring and analyte measurement, comprising:
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a. An arterial catheter, configured to be placed in fluid communication with an artery of a patient; b. A blood access subsystem, comprising;
an analyte measurement device;
a pressure sensor;
a fluid path from the arterial catheter to the analyte measurement device and to the pressure sensor;
at least one pump configured to move fluid in the fluid pathways; and
a control system operatively connected to the pump to control operation of the pump; andc. A pressure determination system responsive to the pressure sensor and to the control system, configured to determine a signal corresponding to pressure in the artery from the pressure sensor and from the characteristics of the pump as indicated by the control system. - View Dependent Claims (12)
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13. An analyte measurement apparatus, comprising:
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a. A blood access subsystem, configured to transport fluid from a fluid access port connected to an arterial catheter during defined fluid transport times; b. An analyte measurement subsystem, configured to determine an analyte property of said withdrawn blood; and c. A pressure signal communication subsystem, configured to accept an input pressure signal from a pressure measurement system in fluid communication with the fluid access port, and to output a signal determined by (i) the input pressure signal except during fluid transport times, and (ii) a determined signal during fluid transport times. - View Dependent Claims (14, 15, 16)
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Specification