ANTIMICROBIAL ARTICLES AND METHOD OF MANUFACTURE

• US 20100098949A1
• Filed: 10/16/2007
• Published: 04/22/2010
• Est. Priority Date: 10/18/2006
• Status: Abandoned Application

• Current Assignee: 3M Innovative Properties Company (3M Company)
• Original Assignee: 3M Innovative Properties Company (3M Company)
• Inventors: Burton, Scott A., Holm, David R.
• Application Number:
  US12/444,877
• Publication Number:
  US 20100098949A1
• Time in Patent Office: Days
• US Class Current: 428/412
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A61L 15/18 containing inorganic materials
• CPC Class Codes: A61L 15/44 Medicaments
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: D06M 11/83 with metals; with metal-generating compounds, e.g. metal carbonyls; Reduction of metal compounds on textiles
• CPC Class Codes: D06M 16/00 Biochemical treatment of fibres, threads, yarns, fabrics, or fibrous goods made from such materials, e.g. enzymatic
• CPC Class Codes: Y10T 428/31507 Of polycarbonate
• CPC Class Codes: Y10T 428/3154 Of fluorinated addition polymer from unsaturated monomers
• CPC Class Codes: Y10T 428/31544 Addition polymer is perhalogenated
• CPC Class Codes: Y10T 428/31609 Particulate metal or metal compound-containing
• CPC Class Codes: Y10T 428/31725 Of polyamide
• CPC Class Codes: Y10T 428/31739 Nylon type
• CPC Class Codes: Y10T 428/31765 Inorganic-containing or next to inorganic-containing
• CPC Class Codes: Y10T 428/31786 Of polyester [e.g., alkyd, etc.]
• CPC Class Codes: Y10T 428/31826 Of natural rubber
• CPC Class Codes: Y10T 428/31935 Ester, halide or nitrile of addition polymer
• CPC Class Codes: Y10T 428/31938 : Polymer of monoethylenically unsaturated hydrocarbon
• CPC Class Codes: Y10T 428/31971 : Of carbohydrate

Abstract

Antimicrobial articles and methods for the manufacture of such articles are provided.

Claims

1. A method of making an antimicrobial article, comprising:

applying a silver composition to a substrate to provide a liquid coated substrate, the silver composition comprising a silver salt other than silver sulfate in a solvent, the silver composition comprising a stabilizing agent in an amount less than about 100 ppm;

the substrate comprising material selected from the group consisting of polyamide, polyester, polyacetate, polyacrylic, polyolefin, polyurethane, polyvinylchloride, polyvinyl alcohol, polycarbonate, polyvinylpyrrolidone, polylactic acid, ethylene-vinyl acetate, polystyrene, cellulose acetate, polyacrylate, polyacrylamide, polyacrylonitrile, polyvinylidene difluoride, polytetrafluoroethylene, polyoxymethylene, polyvinyl ether, styrene-ethylenebutylene-styrene elastomer, styrene-butylene-styrene elastomer, styrene-isoprene-styrene elastomer, glass fiber, ceramic and combinations of two or more of the foregoing; and

drying the liquid coated substrate to provide a color stable antimicrobial article comprising silver salt applied to the substrate.

2. The method of claim 1, wherein the silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver lactate, silver nitrate, silver nitrite, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver levunilate, silver propionate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

5. The method of claim 1, wherein the silver salt is selected from the group consisting of silver iodate, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver hyponitrite, silver myristate, silver palmitate, silver stearate and combinations of two or more of the foregoing.

6. The method of claim 1, wherein the substrate comprises polyolefin selected from the group consisting of polypropylene, polyethylene, ethylene propylene copolymers, ethylene butylene copolymers, and combinations of two or more of the foregoing.

10. The method of claim 1, wherein the silver composition comprises a stabilizing agent in an amount less than 50 ppm based on the total weight of the silver salt composition.

11. The method of claim 1, wherein the silver composition comprises no stabilizing agent.

12. The method of claim 1, wherein drying the liquid coated substrate is accomplished at room temperature.

13. The method of claim 1, wherein drying the liquid coated substrate is accomplished a temperature less than about 100°

C.

14. The method of claim 1 wherein the color stable antimicrobial article comprises silver salt applied to the substrate with a concentration of silver on the substrate being less than about 40,000 mg Ag/kg substrate.

16. The method of claim 1 wherein the color stable antimicrobial article comprises silver salt applied to the substrate with a concentration of silver on the substrate being less than about 10,000 mg Ag/kg substrate.

3. (canceled)

4. (canceled)

7. (canceled)

8. (canceled)

9. (canceled)

15. (canceled)

17. An article, comprising:

a silver salt other than silver sulfate, the silver salt applied to a substrate; and

the substrate comprising material selected from the group consisting of polyamide, polyester, polyacetate, polyacrylic, polyolefin, polyurethane, polyvinylchloride, polyvinyl alcohol, polycarbonate, polyvinylpyrrolidone, polylactic acid, ethylene-vinyl acetate, polystyrene, cellulose acetate, polyacrylate, polyacrylamide, polyacrylonitrile, polyvinylidene difluoride, polytetrafluoroethylene, polyoxymethylene, polyvinyl ether, styrene-ethylenebutylene-styrene elastomer, styrene-butylene-styrene elastomer, styrene-isoprene-styrene elastomer, glass fiber, ceramic and combinations of two or more of the foregoing; and

wherein the article is antimicrobial and color stable.

18. The article of claim 17 wherein the silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver iodate, silver lactate, silver nitrate, silver nitrite, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver hyponitrite, silver levunilate, silver myristate, silver palmitate, silver propionate, silver stearate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

19. The article of claim 18, wherein the silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver lactate, silver nitrate, silver nitrite, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver levunilate, silver propionate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

22. The article of claim 18, wherein the silver salt is selected from the group consisting of silver iodate, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver hyponitrite, silver myristate, silver palmitate, silver stearate and combinations of two or more of the foregoing.

25. The article of claim 17, wherein the concentration of silver on the substrate is less than about 40,000 mg Ag/kg substrate.

27. The article of claim 25, wherein the concentration of silver on the substrate is less than about 40,000 mg Ag/kg substrate.

30. The article of claim 17, wherein the concentration of a stabilizing agent is less than about 100 ppm, based on the total weight of the article.

20. (canceled)

21. (canceled)

23. (canceled)

24. (canceled)

26. (canceled)

28. (canceled)

29. (canceled)

32-48. -48. (canceled)

49. A method of making an antimicrobial article, comprising:

applying a silver composition to a substrate to provide a liquid coated substrate, the silver composition comprising a silver salt other than silver sulfate; and

heating the liquid coated substrate at a temperature sufficient to form silver metal from silver salt to provide a color stable antimicrobial article comprising silver metal nanoparticles and silver salt.

31. The method of claim 49, wherein the silver composition to a substrate to provide a liquid coated substrate, the silver composition comprising a silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver iodate, silver lactate, silver nitrate, silver nitrite, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver hyponitrite, silver levunilate, silver myristate, silver palmitate, silver propionate, silver stearate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

50. The method of claim 49, wherein the silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver lactate, silver nitrate, silver nitrite, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver levunilate, silver propionate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

53. The method of claim 49, wherein the silver salt is selected from the group consisting of silver iodate, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver hyponitrite, silver myristate, silver palmitate, silver stearate and combinations of two or more of the foregoing.

54. The method of claim 49, wherein the substrate comprises material selected from the group consisting of cellulosic material, nylon, polyamides, polyacetates, collagen, gelatin, polyacrylamide, natural rubber, alginates and combinations of two or more of the foregoing.

55. The method of claim 54, wherein the substrate also comprises material selected from the group consisting of polyesters, polyacrylics, polyolefins, polyurethanes, polyvinylchloride, polystyrenes, fiberglass, ceramic fibers, polyacrylate, polyacrylonitrile, polyvinylidene difluoride, polytetrafluoroethylene, polyoxymethylene, polyvinyl alcohol, polylactic acid, polyvinyl ether, polyvinylpyrrolidone, polycarbonate, styrene-ethylenebutylene-styrene elastomer, styrene-butylene-styrene elastomer, styrene-isoprene-styrene elastomer, and combinations of two or more of the foregoing.

57. The method of claim 54, wherein the cellulosic material comprises absorbent carboxymethylated materials selected from the group consisting of carboxymethylated cotton, carboxymethylated cellulose, carboxymethylated solvent-spun cellulose fibers, and carboxymethylated rayon and combinations of two or more of the foregoing.

58. The method of claim 54, wherein the cellulosic material is selected from the group consisting of cotton, rayon, hemp, jute, bamboo fibers, cellulose acetate, carboxymethylated solvent-spun cellulose fibers and combinations of two or more of the foregoing.

60. The method of claim 49, wherein heating the liquid coated substrate is accomplished at a temperature within the range from about 95°

C. to about 225°

C.

63. The method of claim 60, wherein heating the liquid coated substrate is accomplished at a temperature within the range from about 130°

C. to about 175°

C.

64. The method of claim 49, wherein the silver salt solution comprises a stabilizing agent in an amount less than 100 ppm based on the total weight of the silver composition.

65. The method of claim 49, wherein the silver salt solution comprises no stabilizing agent.

66. The method of claim 49, wherein the antimicrobial article is color stable having a non-white color.

51. (canceled)

52. (canceled)

56. (canceled)

59. (canceled)

61. (canceled)

62. (canceled)

67-81. -81. (canceled)

82. An article, comprising:

a silver metal and silver salt applied to a substrate, the silver salt comprising a silver salt other than silver sulfate.

83. The article of claim 82, wherein the silver salt is selected from the group consisting of silver acetate, silver benzoate, silver carbonate, silver chloride, silver citrate, silver lactate, silver nitrate, silver nitrite, silver chlorite, silver fluosilicate, silver trihydrogen paraperiodate, silver levunilate, silver propionate, silver tartrate, mild silver protein, silver protein and combinations of two or more of the foregoing.

86. The article of claim 82, wherein the silver salt is selected from the group consisting of silver iodate, silver oxalate, silver phosphate, silver sulfadiazine, silver saccharinate, silver anthranilate, silver hyponitrite, silver myristate, silver palmitate, silver stearate and combinations of two or more of the foregoing.

87. The article of claim 82, wherein the substrate comprises a material selected from the group consisting of cellulosic material, nylon, polyamides, polyacetates, collagen, gelatin, polyacrylamide, natural rubber, alginates and combinations of two or more of the foregoing.

88. The article of claim 87, wherein the substrate also comprises material selected from the group consisting of polyesters, polyacrylics, polyolefins, polyurethanes, polyvinylchloride, polystyrenes, fiberglass, ceramic fibers, polyacrylate, polyacrylonitrile, polyvinylidene difluoride, polytetrafluoroethylene, polyoxymethylene, polyvinyl alcohol, polylactic acid, polyvinyl ether, polyvinylpyrrolidone, polycarbonate, styrene-ethylenebutylene-styrene elastomer, styrene-butylene-styrene elastomer, styrene-isoprene-styrene elastomer and combinations of two or more of the foregoing.

90. The article of claim 87, wherein the cellulosic material comprise absorbent carboxymethylated materials selected from the group consisting of carboxymethylated cotton, carboxymethylated cellulose, carboxymethylated solvent-spun cellulose fibers, and carboxymethylated rayon and combinations of two or more of the foregoing.

91. The article of claim 87, wherein the cellulosic material is selected from the group consisting of cotton, rayon, hemp, jute, bamboo fibers, cellulose acetate, carboxymethylated solvent-spun cellulose fibers and combinations of two or more of the foregoing.

93. The article of claim 82, wherein the antimicrobial article is color stable having a non-white color.

94. The article of claim 82, wherein the concentration of silver on the substrate is less than about 40,000 mg Ag/kg substrate.

95. The article of claim 82, wherein the concentration of silver on the substrate is less than about 20,000 mg Ag/kg substrate.

96. The article of claim 82, wherein the concentration of silver on the substrate is less than about 10,000 mg Ag/kg substrate.

84. (canceled)

85. (canceled)

89. (canceled)

92. (canceled)