Method of treating diabetes-related vascular complications

• US 20100099751A1
• Filed: 10/21/2008
• Published: 04/22/2010
• Est. Priority Date: 10/21/2008
• Status: Abandoned Application

• Current Assignee: Al-Mulla Fahd, Bitar Milad
• Original Assignee: Al-Mulla Fahd, Bitar Milad
• Inventors: Fahd, Al-Mulla, Milad, Bitar
• Application Number:
  US12/289,146
• Publication Number:
  US 20100099751A1
• Time in Patent Office: Days
• US Class Current: 514/440
• CPC Class Codes: A61K 31/385 having two or more sulfur atoms in the same ring
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

A method of treating diabetes-related vascular complications is provided. It has been found that a heightened state of oxidative stress, either acting alone or in concert with augmented apoptotic and inflammatory processes, contributes to diabetes-related vascular dysfunction. The method of treating diabetes-related vascular complications includes the treatment of diabetic patients with alpha-lipoic acid (LA) in order to mitigate the negative impact of diabetes-related vascular dysfunctions upon vascular homeostasis. The treatment method includes the step of administering to the patient a therapeutically effective dosage of alpha-lipoic acid.

Claims

1. A method of treating diabetes-related vascular complications, comprising the step of administering to a patient a therapeutically effective dosage of alpha-lipoic acid or pharmaceutically acceptable salts thereof for the treatment of diabetes-related vascular complications.

2. The method of treating diabetes-related vascular complications as recited in claim 1, wherein the step of administering to the patient the therapeutically effective dosage of alpha-lipoic acid includes delivery of the alpha-lipoic acid to the patient through oral delivery.

3. The method of treating diabetes-related vascular complications as recited in claim 2, wherein the alpha-lipoic acid is delivered to the patient in a dosage of between approximately 100 mg. and 300 mg.