DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS
First Claim
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1. A device for measuring a glucose concentration in a host, the device comprising:
- a sensing mechanism operably connected to an electronic circuit and configured to continuously measure a signal associated with a glucose concentration in a host for a period of time; and
a membrane located over at least a portion of the sensing mechanism, wherein the membrane is configured to control a flux of oxygen and glucose;
wherein the device is capable of exhibiting, at a glucose concentration of about 400 mg/dL, no more than a 10% drop in sensor output over a range of pO2 from about 150 mm Hg down to about 30 mm Hg.
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Abstract
Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.
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Citations
23 Claims
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1. A device for measuring a glucose concentration in a host, the device comprising:
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a sensing mechanism operably connected to an electronic circuit and configured to continuously measure a signal associated with a glucose concentration in a host for a period of time; and a membrane located over at least a portion of the sensing mechanism, wherein the membrane is configured to control a flux of oxygen and glucose; wherein the device is capable of exhibiting, at a glucose concentration of about 400 mg/dL, no more than a 10% drop in sensor output over a range of pO2 from about 150 mm Hg down to about 30 mm Hg. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification