Radiotherapy Treatment Monitoring Using Ultrasound
2 Assignments
0 Petitions
Accused Products
Abstract
Methods and systems for assessing the effects of therapy on a patient include obtaining baseline and treatment ultrasound scans of a treatment area of a patient where the treatment ultrasound scans are taken subsequent to the baseline scan and at various times during a course of radiotherapy treatment sessions. The baseline and treatment ultrasounds are compared, and as a result a damage map representing cell death within the treatment area can be constructed.
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Citations
57 Claims
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1-32. -32. (canceled)
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33. A method of assessing cell condition in response to treatment, the method comprising the steps of:
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a. obtaining a baseline ultrasound scan of a treatment area of a patient; b. obtaining, subsequent to the baseline scan, one or more temporally distinct treatment ultrasound scans of the treatment area at various times during a course of treatment sessions; c. comparing at least one of the one or more treatment ultrasound scans to the baseline ultrasound scan; and d. based on the comparison, constructing one or more damage maps representing cell damage within the treatment area thereby providing a predictive model of tissue damage due to the treatment. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
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51. A system for determining cell condition in response to treatment, the system comprising:
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a storage unit for receiving ultrasound scans of a treatment area, the ultrasound scans comprising; a baseline ultrasound scan; and one or more temporally distinct treatment ultrasound scans of the treatment area taken subsequent to the baseline scan and at various times during a course of treatment sessions; and a comparator module for; (i) comparing the baseline ultrasound scan and at least one of the one or more treatment ultrasound scans (ii) based on the comparison, constructing a plurality of damage maps representing cell condition within the treatment area, thereby providing a predictive model of tissue damage due to the treatment. - View Dependent Claims (52, 53, 54)
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55. An article of manufacture having computer-readable programs embodied thereon for determining cell condition in response to treatment, the article comprising computer-readable instructions for:
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a. obtaining a plurality of temporally distinct ultrasound scans of a treatment area at various times during a course of treatment sessions; b. comparing the plurality of ultrasound scans; c. constructing a series of damage maps representing cell condition within the treatment area based on the comparison; and d. constructing a predictive model of tissue damage due to treatment based on the series of damage maps. - View Dependent Claims (56, 57)
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Specification