ANALYZING BIOLOGICAL CELL MATERIAL BASED ON DIFFERENT INTERACTIONS BETWEEN ILLUMINATION LIGHT AND CELL COMPONENTS
First Claim
1. A device for analyzing biological cell material (115, 215, 315, 415), the device comprising:
- a light source arrangement (120, 220, 320, 420), which is adapted for directing a first illumination light (131, 231, 331, 431) and a second illumination light (132, 232, 332, 432) towards the biological cell material (115, 215, 315, 415), wherein the first illumination light (131, 231, 331, 431) comprises a first spectral radiation component and the second illumination light (132, 232, 332, 432) comprises a second spectral radiation component,a detector arrangement (170, 270, 370, 470), which is adapted for receivinga first measurement light (151, 251, 351, 451), which is based on a first interaction of the first illumination light (131, 231, 331, 431) with the cell material (115, 215, 315, 415), anda second measurement light (132, 232, 332, 432), which is based on a second interaction of the second illumination light (132, 232, 332, 432) with the cell material (115, 215, 315, 415), and,an evaluation unit (180, 280, 380, 480), which is coupled the detector arrangement (170, 270, 370, 470) and which is adapted to evaluatea first signal (171a, 271a, 371a, 471a) being indicative for the first measurement light (151, 251, 351, 451) anda second signal (172a, 272a, 372a, 472a) being indicative for the second measurement light (132, 232, 332, 432).
1 Assignment
0 Petitions
Accused Products
Abstract
It is described a device (100) for analyzing biological cell material (115). The device (100) comprises a light source arrangement (120), which is adapted for directing a first (131) and a second illumination light (132) towards the cell material (115), wherein the first (131) and the second (132) illumination light comprises a first and a second spectral radiation component, respectively. The device (100) further comprises a detector arrangement (170), which is adapted for receiving a first measurement light (151) based on a first interaction of the first illumination light (131) with the cell material (115) and a second measurement light (152) based on a second interaction of the second illumination light (152) with the cell material (115). Further, the device (100) comprises an evaluation unit (180), which is coupled the detector arrangement (170) and which is adapted to evaluate a first signal (171a) and a second signal (171b) being indicative for the first (151) and the second measurement light (151), respectively. The device (100) may be used for accomplishing ultraviolet DNA image cytometryin combination with autofluorescence measurements of NAD(P)H.
-
Citations
16 Claims
-
1. A device for analyzing biological cell material (115, 215, 315, 415), the device comprising:
-
a light source arrangement (120, 220, 320, 420), which is adapted for directing a first illumination light (131, 231, 331, 431) and a second illumination light (132, 232, 332, 432) towards the biological cell material (115, 215, 315, 415), wherein the first illumination light (131, 231, 331, 431) comprises a first spectral radiation component and the second illumination light (132, 232, 332, 432) comprises a second spectral radiation component, a detector arrangement (170, 270, 370, 470), which is adapted for receiving a first measurement light (151, 251, 351, 451), which is based on a first interaction of the first illumination light (131, 231, 331, 431) with the cell material (115, 215, 315, 415), and a second measurement light (132, 232, 332, 432), which is based on a second interaction of the second illumination light (132, 232, 332, 432) with the cell material (115, 215, 315, 415), and, an evaluation unit (180, 280, 380, 480), which is coupled the detector arrangement (170, 270, 370, 470) and which is adapted to evaluate a first signal (171a, 271a, 371a, 471a) being indicative for the first measurement light (151, 251, 351, 451) and a second signal (172a, 272a, 372a, 472a) being indicative for the second measurement light (132, 232, 332, 432). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. A method for analyzing biological cell material (115, 215, 315, 415), the method comprising
directing a first illumination light (131, 231, 331, 431) comprising a first spectral radiation component from a light source arrangement (120, 220, 320, 420) towards the cell material (115, 215, 315, 415), directing a second illumination light (132, 232, 332, 432) comprising a second spectral radiation component from the light source arrangement (120, 220, 320, 420) towards the cell material (115, 215, 315, 415), receiving a first measurement light (151, 251, 351, 451), which is based on a first interaction of the first illumination light (131, 231, 331, 431) with the cell material (115, 215, 315, 415), by means of a detector arrangement (170, 270, 370, 470), receiving a second measurement light (132, 232, 332, 432), which is based on a second interaction of the second illumination light (132, 232, 332, 432) with the cell material (115, 215, 315, 415), by means of the detector arrangement (170, 270, 370, 470), evaluating a first signal being indicative for the first measurement light (151, 251, 351, 451), and evaluating a second signal being indicative for the second measurement light (132, 232, 332, 432).
Specification