METHOD AND DEVICE FOR DETERMINING CARDIAC OUTPUT WITH CARBON DIOXIDE PARTIAL RE-BREATHING

• US 20100106037A1
• Filed: 03/05/2008
• Published: 04/29/2010
• Est. Priority Date: 03/07/2007
• Status: Abandoned Application

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Jiang, Yandong, Liang, Yafen, Kacmarek, Robert M.
• Application Number:
  US12/530,397
• Publication Number:
  US 20100106037A1
• Time in Patent Office: Days
• US Class Current: 600/526
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61M 16/0045 Means for re-breathing exhaled gases, e.g. for hyperventilation treatment
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0833 T- or Y-type connectors, e.g. Y-piece
• CPC Class Codes: A61M 16/20 Valves specially adapted to medical respiratory devices
• CPC Class Codes: A61M 2016/003 with a flowmeter
• CPC Class Codes: A61M 2230/432 partial CO2 pressure (P-CO2)

Abstract

A method and apparatus (10) for determining cardiac output by directing airflow or gas flow (fluid) to a fluid containment structure (12) coupled to an inspiratory limb (16) of a ventilator circuit instead of the patient and enabling the patient to directly inhale fluid from the fluid containment structure and preventing the patient from inhaling through an expiratory limb (18) of the ventilator-circuit. The method and apparatus also prevents exhalation by the patient into the fluid containment structure. The method and apparatus also comprises an aid helps the patient become consistent in their breathing patterns. When the fluid containment structure fills with a volume of fluid, the aid provides an indication that the patient should inhale; when the fluid containment structure empties of fluid, the aid provides a signal that the patient should exhale. Thus, the aid provides feedback to the patient to help the patient control their ventilation pattern.

Claims

1. A device comprising:

an oral-nasal face mask;

a ventilator having a first port;

a ventilator circuit in fluid communication with said oral-nasal face mask, said ventilator circuit having an inspiratory limb having a port coupled to said ventilator and an expiratory limb having a port;

a fluid containment structure having a first port in fluid communication with the inspiratory limb of said ventilator circuit and having a second port;

an airflow direction system in fluid communication with the inspiratory and expiratory limbs of said ventilator circuit, said airflow direction system coupled to allow gas to only fill the fluid containment structure at a first point in time and to allow a patient to breathe gas only from the a fluid containment structure; and

a non-invasive cardiac output (NICO) monitor coupled to the ventilator circuit;

2. The device of claim 1 wherein said ventilator circuit comprises a y-piece having a first path corresponding to the inspiratory limb of the ventilator circuit, a second path corresponding to the expiratory limb of the ventilator circuit and a third path adapted to couple to a rebreathing valve.

3. The device of claim 1 wherein said airflow direction system comprises:

a first valve disposed in the inspiratory limb of the ventilator circuit, said first valve having a first port in fluid communication with the ventilator and a second port in fluid communication with a first port of the fluid containment structure;

a second valve disposed in the inspiratory limb of the ventilator circuit, said second valve having a first port in fluid communication with a second port of the fluid containment structure and a second port in fluid communication with the third path; and

a third valve disposed in the expiratory limb of the ventilator circuit.

4. The device of claim 1 wherein

said first valve is in fluid communication with and positioned between the ventilator and the fluid containment structure and operable to allow a patient to inhale gas only from the fluid containment structure;

said second valve is in fluid communication with and positioned in the inspiratory limb of said ventilator circuit between the fluid containment structure and the Y-piece and is operable to deliver a targeted volume of gas to the fluid containment structure only, but not to the patient wherein the first and second valves open in alternated order, but not at the same time; and

said third valve is in fluid communication with the expiratory limb 18 and operable to prevent the patient from inhaling gas from the expiratory limb of the ventilator circuit.

5. A method comprising:

applying a ventilator circuit to a patient'"'"'s natural airway using an oral-nasal face mask.

delivering mechanical ventilation with a specific predetermined tidal volume and ventilatory rate;

measuring cardiac output (CO) with a non-invasive cardiac output (NICO) monitor using a NICO technique.

6. The method of claim 5 wherein delivering mechanical ventilation with a specific predetermined tidal volume and ventilatory rate comprises;

operating a first valve in fluid communication with and positioned between the ventilator and the fluid containment structure to fill the fluid containment structure with gas and to allow a patient to inhale gas only from the fluid containment structure;

operating a second valve in fluid communication with and positioned in the inspiratory limb of the ventilator circuit between the fluid containment structure and the Y-piece to deliver a targeted volume of gas to the fluid containment structure only, but not to the patient wherein the first and second valves open in alternating order, but not at the same time; and

operating a third valve in fluid communication with the expiratory limb to prevent the patient from inhaling gas from the expiratory limb of the ventilator circuit.

7. The method of claim 6 further comprising monitoring respiratory parameters of a patient.

8. A method comprising:

having a patient breath normally through an oral-nasal face mask and a non-invasive cardiac output (NICO) monitor without attachment to a ventilator until their ventilatory pattern is stable;

measuring the patient'"'"'s tidal volume, respiratory rate and minute ventilation;

computing the average tidal volume and respiratory rate;

attaching the ventilator to the NICO monitor and operating the ventilator to provide volume targeted mechanical ventilation to a fluid containment structure; and

holding the patient'"'"'s minute volume and carbon dioxide (CO₂) elimination constant.

9. The method of claim 8 further wherein operating the ventilator to provide volume targeted mechanical ventilation to a fluid containment structure comprises operating the ventilator to provide volume targeted mechanical ventilation to a fluid containment structure with the ventilator set at or slightly above the patient'"'"'s average tidal volume and respiratory rate.

10. The method of claim 8 further wherein operating the ventilator to provide volume targeted mechanical ventilation to a fluid containment structure comprises operating a plurality of valves to fill the fluid containment structure with gas and to allow a patient to inhale gas only from the fluid containment structure and to prevent the patient from inhaling gas from any other portion of the ventilator circuit.

11. The method of claim 8 further comprising monitoring respiratory parameters of the patient.

12. A method comprising:

ventilating a fluid containment structure in fluid communication with an inspiratory limb of a ventilator circuit; and

having a patient passively inspire a fixed volume of gas only from the fluid containment structure wherein the fluid containment structure prevents ventilator pressure from being applied directly to the patient'"'"'s airway such that a ventilatory pattern is maintained consistent and a cardiac output of the patient is prevented from being altered by the application of positive pressure.

13. The method of claim 12 wherein ventilating a fluid containment structure comprises ventilating one of:

a balloon, a syringe and a bellows.

14. A method for determining cardiac output of a patient, the method comprising:

operating an airflow direction system to allow a fluid containment structure to be filled with a substantially predetermined volume of gas;

providing an indication that the fluid containment structure is filled with the substantially predetermined volume of gas; and

in response to the indication that the fluid containment structure is filled with the substantially predetermined volume of gas, allowing the patient to inhale the volume of gas from the fluid containment structure.

15. The method of claim 14 further comprising:

providing an indication that the substantially predetermined volume of gas has been emptied from the fluid containment structure; and

in response to the indication that the substantially predetermined volume of gas has been emptied from the fluid containment structure, allowing the patient to exhale.

16. The method of claim 14 wherein providing an indication that the fluid containment structure is filled with the substantially predetermined volume of gas comprises providing a visual indication that the fluid containment structure is filled with the substantially predetermined volume of gas.

17. The method of claim 16 wherein the fluid containment structure corresponds to a balloon and the visual indication of the fluid containment structure being filled with the substantially predetermined volume of gas is provided by the shape and size of the balloon.

18. The method of claim 17 wherein the visual indication of the fluid containment structure not being filled with gas is provided by the shape and size of the balloon.

19. The method if claim 14 wherein the fluid containment structure provides visual feedback of when it is filled with and empty of gas and also provides the patient with a visual target such that patients can easily keep up with the visual target and maintain a substantially constant tidal volume constant.