Examination Device for Blood Detection
First Claim
Patent Images
1. An examination device for detecting the presence of blood in a sample, comprising:
- a first finger receiving member having a first open end, a second closed end, and a sample collection area generally located proximal said second closed end thereof for receiving a sample to be tested for the presence of blood, anda second finger receiving member located spaced apart from said first finger receiving member and having a first open end, a second closed end, and one or more pressure rupturable encapsulations containing at least one reagent capable of reacting with a blood component,wherein, when a sample containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member by rupturing said one or more pressure rupturable encapsulations, a visible indication that said sample contains blood results at said second finger receiving member, andwherein, when a sample not containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member by rupturing said one or more pressure rupturable encapsulations, a visible indication that said sample contains blood does not result at said second finger receiving member.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention describes examination devices, such as examination gloves, for detecting the presence of blood, and in particular hidden blood, in biological samples. Examination devices according to the present invention include, in certain embodiments, developer and indicator reagents in a single encapsulation and in microencapsulations, which offers numerous clinical and other benefits. Kits including devices according to the present invention in sterile packaging, and methods of making and using devices according to the present invention, are also described.
-
Citations
21 Claims
-
1. An examination device for detecting the presence of blood in a sample, comprising:
-
a first finger receiving member having a first open end, a second closed end, and a sample collection area generally located proximal said second closed end thereof for receiving a sample to be tested for the presence of blood, and a second finger receiving member located spaced apart from said first finger receiving member and having a first open end, a second closed end, and one or more pressure rupturable encapsulations containing at least one reagent capable of reacting with a blood component, wherein, when a sample containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member by rupturing said one or more pressure rupturable encapsulations, a visible indication that said sample contains blood results at said second finger receiving member, and wherein, when a sample not containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member by rupturing said one or more pressure rupturable encapsulations, a visible indication that said sample contains blood does not result at said second finger receiving member. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. An examination glove for detecting the presence of blood in a sample, comprising:
-
a first finger receiving member having a first open end, a second closed end, and a sample collection area generally located proximal said second closed end thereof for receiving a sample to be tested for the presence of blood, and a second finger receiving member located spaced apart from said first finger receiving member and having a first open end, a second closed end, and a microencapsulation array including pressure rupturable microcapsules containing at least one reagent capable of reacting with a blood component, wherein. when a sample containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member by rupturing said microcapsules, a visible indication that said sample contains blood results at said second finger receiving member, and wherein, when a sample not containing blood is received at said sample collection area of said first finger receiving member and caused to contact said at least one reagent at said second finger receiving member, a visible indication that said sample contains blood does not result at said second finger receiving member. - View Dependent Claims (18, 19, 20)
-
-
21. A microencapsulation array for use in detecting the presence of blood in a sample, comprising:
-
a substrate layer; pressure rupturable microcapsules affixed to said substrate layer, said pressure rupturable microcapsules containing a first reagent selected from a developer reagent and an indicator reagent; a pad positioned opposite said substrate layer such that said pressure rupturable microcapsules are generally located in-between said substrate layer and said pad, and wherein said pad is impregnated with a second reagent that is different from said first reagent and is selected from a developer reagent and said indicator reagent, wherein, said first reagent is absorbed into said pad upon rupture of said microcapsules.
-
Specification