Compositions and methods for surface abrasion with frozen particles
2 Assignments
0 Petitions
Accused Products
Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
101 Citations
165 Claims
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1-74. -74. (canceled)
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75. A method for abrasion of at least one biological tissue surface of a subject, comprising:
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delivering at least one composition to at least one surface of at least one biological tissue of a subject in a manner sufficient to abrade the at least one surface of the at least one biological tissue; wherein the at least one composition includes one or more frozen hydrogen oxide particles, wherein the one or more frozen hydrogen oxide particles have at least one major dimension of approximately one centimeter or less; and wherein the one or more frozen hydrogen oxide particles are in one or more phases including amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, or ice XIV. - View Dependent Claims (76, 77, 78, 79, 82, 84, 85, 86, 88, 94, 96, 98, 100, 101, 102, 103, 105, 110, 114, 115, 116, 118, 120, 121, 123, 124, 126, 129)
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80-81. -81. (canceled)
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83. (canceled)
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87. (canceled)
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89-93. -93. (canceled)
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99. (canceled)
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104. (canceled)
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106-109. -109. (canceled)
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111-113. -113. (canceled)
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117. (canceled)
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122. (canceled)
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125. (canceled)
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127-128. -128. (canceled)
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130. (canceled)
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131. A method for debridement of at least one biological tissue of a subject, comprising:
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delivering at least one composition to at least one biological tissue of a subject in a manner sufficient to remove dead, damaged or infected tissue of the at least one biological tissue, wherein the at least one composition includes one or more frozen hydrogen oxide particles, wherein the one or more frozen hydrogen oxide particles have at least one major dimension of approximately one centimeter or less; and wherein the one or more frozen hydrogen oxide particles are in one or more phases including amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, or ice XIV. - View Dependent Claims (132, 133, 134, 139, 144, 145)
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135-138. -138. (canceled)
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140-143. -143. (canceled)
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146. A method for removing one or more materials from at least one blood vessel of at least one subject, comprising:
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delivering at least one composition to at least one blood vessel of a subject in a manner sufficient to remove one or more materials, wherein the at least one composition includes one or more frozen hydrogen oxide particles, wherein the one or more frozen hydrogen oxide particles have at least one major dimension of approximately one centimeter or less; and
wherein the one or more frozen hydrogen oxide particles are in one or more phases including amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, or ice XIV;wherein the one or more frozen particles have at least one major dimension of approximately one centimeter or less. - View Dependent Claims (148, 154, 155)
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147. (canceled)
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149-153. -153. (canceled)
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156. (canceled)
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157. A method for cleaning one or more wounds of a subject, comprising:
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delivering at least one composition to one or more wounds in a manner sufficient to clean the one or more wounds, wherein the at least one composition includes one or more frozen hydrogen oxide particles, wherein the one or more frozen hydrogen oxide particles are in one or more phases including amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, or ice XIV wherein the one or more frozen particles have at least one major dimension of approximately one centimeter or less. - View Dependent Claims (158, 160, 161, 162)
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159. (canceled)
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163. (canceled)
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164. A method for abrasion of at least one biological tissue or organ surface related to transplantation, comprising:
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delivering at least one composition to at least one surface of at least one tissue or organ in a manner sufficient to abrade the at least one surface of the at least one biological tissue, wherein the at least one composition includes one or more frozen hydrogen oxide particles, wherein the one or more frozen hydrogen oxide particles are in one or more phases including amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, or ice XIV, wherein the one or more frozen hydrogen oxide particles have at least one major dimension of approximately one centimeter or less.
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165-168. -168. (canceled)
Specification