Compositions and methods for therapeutic delivery with frozen particles
1 Assignment
0 Petitions
Accused Products
Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
107 Citations
152 Claims
-
1-42. -42. (canceled)
-
43. A method of providing at least one therapeutic agent to at least one biological tissue of a subject, comprising:
-
delivering at least one therapeutic composition to at least one biological tissue, wherein the at least one therapeutic composition includes one or more frozen hydrogen oxide particles and at least one therapeutic agent; wherein the one or more frozen particles are in one or more phases including at least one of amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, ice XIV, or ice XV. - View Dependent Claims (46, 49, 51, 52, 53, 55, 60, 61, 63, 64, 65, 66, 68, 73, 77, 78, 79, 81, 83, 86, 87, 89, 90, 93, 94)
-
-
44-45. -45. (canceled)
-
47-48. -48. (canceled)
-
50. (canceled)
-
54. (canceled)
-
56-59. -59. (canceled)
-
62. (canceled)
-
67. (canceled)
-
69-72. -72. (canceled)
-
74-76. -76. (canceled)
-
80. (canceled)
-
82. (canceled)
-
84-85. -85. (canceled)
-
88. (canceled)
-
91-92. -92. (canceled)
-
95. A method of vaccinating a subject, comprising:
-
administering to a subject at least one therapeutic composition; wherein the at least one therapeutic composition includes one or more frozen hydrogen oxide particles including at least one vaccine, and wherein the one or more frozen particles have one or more phases including at least one of amorphous solid water, low density amorphous ice, high density amorphous ice, very high density amorphous ice, clathrate ice, hyperquenched glassy water, ice Ic, ice II, ice III, ice IV, ice V, ice VI, ice VII, ice VIII, ice IX, ice X, ice XI, ice XII, ice XIII, ice XIV, or ice XV. - View Dependent Claims (97, 98, 100, 103, 104, 107, 109, 110, 113, 118, 119, 121, 122, 123, 124, 126, 131, 135, 136, 137, 139, 144, 145, 147, 148, 150, 151)
-
-
96. (canceled)
-
99. (canceled)
-
101-102. -102. (canceled)
-
105-106. -106. (canceled)
-
108. (canceled)
-
111-112. -112. (canceled)
-
114-117. -117. (canceled)
-
120. (canceled)
-
125. (canceled)
-
127-130. -130. (canceled)
-
132-134. -134. (canceled)
-
138. (canceled)
-
140-143. -143. (canceled)
-
146. (canceled)
-
149. (canceled)
-
152. (canceled)
Specification