Compositions and methods for administering compartmentalized frozen particles
First Claim
Patent Images
1. A frozen particle composition, comprising:
- a frozen particle defining at least one cavity;
the at least one cavity containing at least one agent; and
wherein the frozen particle includes at least one component that is in a gaseous state at or above approximately 0.25 bar, approximately 0.5 bar, approximately 1.0 bar, approximately 5.0 bar, approximately 10.0 bar, approximately 25 bar, approximately 50 bar, approximately 100 bar, approximately 200 bar, or approximately 500 bar pressure; and
at or above approximately 10°
C., approximately 15°
C., approximately 20°
C., approximately 25°
C., approximately 30°
C., approximately 37°
C., approximately 40°
C., approximately 45°
C., approximately 50°
C.
3 Assignments
0 Petitions
Accused Products
Abstract
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
118 Citations
171 Claims
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1. A frozen particle composition, comprising:
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a frozen particle defining at least one cavity; the at least one cavity containing at least one agent; and wherein the frozen particle includes at least one component that is in a gaseous state at or above approximately 0.25 bar, approximately 0.5 bar, approximately 1.0 bar, approximately 5.0 bar, approximately 10.0 bar, approximately 25 bar, approximately 50 bar, approximately 100 bar, approximately 200 bar, or approximately 500 bar pressure; and
at or above approximately 10°
C., approximately 15°
C., approximately 20°
C., approximately 25°
C., approximately 30°
C., approximately 37°
C., approximately 40°
C., approximately 45°
C., approximately 50°
C. - View Dependent Claims (2, 3, 4, 10, 11, 13, 23, 24, 39, 40, 43, 46, 47, 48, 49, 51, 52, 53, 54, 59, 60, 61)
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5-9. -9. (canceled)
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12. (canceled)
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14-22. -22. (canceled)
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25-38. -38. (canceled)
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41-42. -42. (canceled)
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44-45. -45. (canceled)
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50. (canceled)
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55-58. -58. (canceled)
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62. A method of providing at least one agent to at least one biological tissue of a subject, comprising:
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administering at least one frozen particle composition to at least one biological tissue, wherein the at least one frozen particle composition includes one or more frozen particles defining at least one cavity; the at least one cavity containing at least one agent; and wherein the frozen particles include at least one component that is in a gaseous state at or above approximately 0.25 bar, approximately 0.5 bar, approximately 1.0 bar, approximately 5.0 bar, approximately 10.0 bar, approximately 25 bar, approximately 50 bar, approximately 100 bar, approximately 200 bar, or approximately 500 bar pressure; and
at or above approximately 10°
C., approximately 15°
C., approximately 20°
C., approximately 25°
C., approximately 30°
C., approximately 37°
C., approximately 40°
C., approximately 45°
C., or approximately 50°
C. - View Dependent Claims (63, 65, 67, 69, 75, 86)
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64. (canceled)
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66. (canceled)
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68. (canceled)
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70-74. -74. (canceled)
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76-85. -85. (canceled)
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87-103. -103. (canceled)
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104. A method of vaccinating a subject, comprising:
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administering at least one frozen particle composition to at least one biological tissue of a subject; wherein the at least one frozen particle composition includes one or more frozen particles defining at least one cavity; the at least one cavity containing at least one vaccine; and wherein the one or more frozen particles include at least one component that is in a gaseous state at or above approximately 0.25 bar, approximately 0.5 bar, approximately 1.0 bar, approximately 5.0 bar, approximately 10.0 bar, approximately 25 bar, approximately 50 bar, approximately 100 bar, approximately 200 bar, or approximately 500 bar pressure; and
at or above approximately 10°
C., approximately 15°
C., approximately 20°
C., approximately 25°
C., approximately 30°
C., approximately 37°
C., approximately 40°
C., approximately 45°
C., or approximately 50°
C. - View Dependent Claims (105, 107, 109, 115, 121, 127, 128, 130, 132, 133)
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106. (canceled)
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134-142. -142. (canceled)
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143. A frozen particle composition, comprising:
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a frozen particle defining at least one cavity configured for holding at least one agent; wherein the frozen particle includes at least one component that is in a gaseous state at or above approximately 0.25 bar, approximately 0.5 bar, approximately 1.0 bar, approximately 5.0 bar, approximately 10.0 bar, approximately 25 bar, approximately 50 bar, approximately 100 bar, approximately 200 bar, or approximately 500 bar pressure; and
at or above approximately 10°
C., approximately 15°
C., approximately 20°
C., approximately 25°
C., approximately 30°
C., approximately 37°
C., approximately 40°
C., approximately 45°
C., or approximately 50°
C. - View Dependent Claims (144, 145, 146, 147, 148, 158, 159, 170)
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149-157. -157. (canceled)
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160-169. -169. (canceled)
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171-186. -186. (canceled)
Specification