DELAYED GELATION COMPOSITIONS AND METHODS OF USE
First Claim
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1. A composition comprising:
- at least one polysaccharide, optionally in solution;
at least one salt, optionally in solution; and
at least one reactive component, optionally in solution,wherein at least one of the polysaccharide, salt and reactive component are in a solution, and wherein the composition forms a gel from about 3 hours to about 5 hours after the at least one polysaccharide, at least one salt, and at least one reactive component have been combined.
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Abstract
Biocompatible compositions are provided which may include at least one polysaccharide, at least one salt, and at least one reactive component. The at least one polysaccharide, at least one salt, and at least one reactive component may be in a single solution or multiple solutions and combined utilizing means within the purview of those skilled in the art. The compositions of the present disclosure experience delayed gelation, permitting their manipulation after application to tissue, which may be desirable for certain surgical and/or medical procedures, including cosmetic surgery.
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Citations
21 Claims
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1. A composition comprising:
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at least one polysaccharide, optionally in solution; at least one salt, optionally in solution; and at least one reactive component, optionally in solution, wherein at least one of the polysaccharide, salt and reactive component are in a solution, and wherein the composition forms a gel from about 3 hours to about 5 hours after the at least one polysaccharide, at least one salt, and at least one reactive component have been combined. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method comprising:
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contacting tissue with at least one polysaccharide, at least one salt, and at least one reactive component; and allowing the at least one polysaccharide, at least one salt, and at least one reactive component to form a gel, wherein the gel forms from about 3 hours to about 5 hours after the at least one polysaccharide, at least one salt, and at least one reactive component have been combined. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A composition comprising:
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at least one polysaccharide comprising sodium alginate; at least one salt comprising calcium carbonate; and at least one reactive component comprising genipin, wherein the composition has a viscosity of from about 0.01 Poise to about 1000 Poise upon combining the at least one polysaccharide, the at least one salt, and the at least one reactive component, and wherein the composition forms a gel from about 3 hours to about 5 hours after the at least one polysaccharide, the at least one salt, and the at least one reactive component, have been combined. - View Dependent Claims (21)
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Specification