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TRANSCRIPTOMIC BIOMARKERS FOR INDIVIDUAL RISK ASSESSMENT IN NEW ONSET HEART FAILURE

  • US 20100112587A1
  • Filed: 11/02/2009
  • Published: 05/06/2010
  • Est. Priority Date: 05/01/2007
  • Status: Abandoned Application
First Claim
Patent Images

1. A molecular composition comprising biomarker molecules:

  • 232669_at (Hypoxia inducible factor 3, alpha subunit), 214951_at (solute carrier family 26, member

         10), 243482_at (Epidermal growth factor receptor pathway substrate 15-like

         1), 226210_s_at (maternally expressed

         3), 232159_at (Epidermal growth factor receptor pathway substrate 15-like

         1), 233026_s_at (PDZ domain containing), 211996_s_at (KIAA0220-like protein hypothetical gene LOC

         283846), 243774_at (mucin 20, cell surface associated), 242551_at (Chromosome 18 open reading frame), 244548_at (Rho GTPase activating protein

         26), 244208_at (Checkpoint suppressor

         1), 239984_at (Sodium channel, voltage-gated, type VII, alpha), 230683_at (cDNA;

    FLJ20892 fis, clone ADKA03430), 214869_at (apolipoprotein L,

         6), 241597_at (Arginine-glutamic acid dipeptide (RE) repeats), 235887_at (5 mg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)), 229957_at (transmembrane protein

         91), 223546_x_at (LUC7L-like (S. cerevisiae)), 239567_at (Rho GTPase activating protein

         10), 242194_at (Cullin 4A), 1558525_at (hypothetical protein LOC283901), 227178_at (CUG triplet repeat, RNA binding protein

         2), 228198_s_at (Mitochondrial ribosomal protein S9), 202379_s_at (natural killer-tumor recognition sequence), 224260_at (cDNA clone), 238643_at (Neuroblastoma, suppression of tumorigenicity

         1), 232253_at (RAD50 homolog (S. cerevisiae)), 227968_at (Parkinson disease 7 domain containing

         1), 233197_at (kelch-like 9 (Drosophila)), 244512_at (transcribed locus strongly similar to XP

    0010813421), 233443_at (hypothetical protein LOC389362), 231275_at (FLJ42875 protein), 226419_s_at (hypothetical protein LOC64546), 201221_s_at small nuclear ribonucleoprotein 70 kDa polypeptide), 209354_at (tumor necrosis factor receptor family member

         14), 226571_s_at (protein tyrosine phosphatase receptor type, S), 220728_at (EST), 203071_at (sema domain, immunoglobulin domain (Ig), short basic domain), 213946_s_at obscurin-like 1, similar to titin isoform N2-B), 201394_s_at (RNA binding motif protein

         5), 203748_x_at (RNA binding motif, single stranded interacting protein

         1), 223147_s_at (WD repeat domain

         33), 213773_x_at (NOL/NOP2/Sun domain family, member

         5), 1560049_at CUG triplet repeat, RNA binding protein

         2), 243974_at (cDNA clone IMAGE;

    4821815), 201510_at E74-like factor 3 (ets domain transcription factor, epithelial specific), complementary sequences, fragments, alleles, variants, derivatives and/or gene products thereof.

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