WOUND GOGGLES

• US 20100113940A1
• Filed: 11/10/2009
• Published: 05/06/2010
• Est. Priority Date: 01/10/2008
• Status: Abandoned Application

• Current Assignee: The Ohio State University Research Foundation
• Original Assignee: The Ohio State University Research Foundation
• Inventors: Sen, Chandan K., Xu, Ronald X.
• Application Number:
  US12/615,950
• Publication Number:
  US 20100113940A1
• Time in Patent Office: Days
• US Class Current: 600/476
• CPC Class Codes: A61B 5/0062 Arrangements for scanning
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14558 by polarisation
• CPC Class Codes: A61B 5/445 Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
• CPC Class Codes: A61B 5/6814 Head
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G01N 2021/6423 Spectral mapping, video display
• CPC Class Codes: G01N 21/49 within a body or fluid
• CPC Class Codes: G01N 21/6456 Spatial resolved fluorescence measurements; Imaging
• CPC Class Codes: G01N 21/6486 Measuring fluorescence of biological material, e.g. DNA, RNA, cells G01N21/6428 takes precedence

Abstract

Appropriate assessment of wound oxygenation is critical to establish a diagnosis, to monitor the effect of the treatment, to guide the therapeutic process, to identify the presence of infection, and to predict the treatment outcome. Embodied systems and methods represent an enabling technology for noninvasive and objective assessment of wound tissue oxygenation. In addition to wound healing, disclosed embodiments offer low cost and portable avenues for noninvasive assessment of multiple clinical parameters for the detection and intervention of various malignancies in multiple soft tissue systems.

Claims

1. A system for visual wound assessment on a subject tissue, comprising:

an illumination unit adapted to emit an excitation light on the subject tissue;

an eyewear unit comprising;

an imaging unit to collect light from the subject tissue; and

an image display unit for displaying a hyperspectral image; and

a control unit operably connected to the eyewear unit and the illumination unit, the control unit comprising;

a light processing module;

an imaging fiber guide to transport emitted light received by the imaging unit to the light processing module; and

a computer programmed to;

synchronize activities of the illumination unit, the imaging unit, the light processing module, and the image display unit; and

generate the hyperspectral image in about real time.

2. The system of claim 1, further comprising:

a backpack containing at least a portion of the control unit.

3. The system of claim 1, wherein:

the imaging unit comprises an automated zoom lens.

4. The system of claim 1, wherein:

the light processing module comprises a CCD camera equipped with a liquid crystal tunable filter and an optical adaptor.

5. The system of claim 4, wherein:

the light processing module further comprises a polarizer.

6. The system of claim 1, wherein:

the illumination unit comprises in alignment;

a spectrally tunable light source; and

a programmable mirror galvanometer adapted to receive and direct excitation light in a point-to-point scanning pattern.

7. The system of claim 1, wherein:

the illumination unit comprises in alignment;

a spectrally tunable light source;

a polarizer;

an optical chopper; and

a shutter.

8. The system of claim 7, wherein:

the illumination unit further comprises in alignment;

a programmable mirror galvanometer adapted to receive and direct excitation light in a point-to-point scanning pattern.

9. The system of claim 1, wherein:

the illumination unit comprises in alignment;

a tunable light source; and

a lens assembly positioned to expand the light for full-field illumination of the subject tissue.

10. The system of claim 6, further comprising:

a cylindrical mirror positioned between the eyewear unit and the subject tissue.

11. The system of claim 6, wherein:

the illumination unit is positioned to provide the excitation light at an oblique angle relative to the subject tissue.

12. An arrangement for visual wound assessment on a subject tissue, comprising:

an illumination unit adapted to emit an excitation light on the subject tissue, the illumination unit comprises in alignment;

a tunable light source; and

a programmable mirror galvanometer adapted to receive and direct excitation light in a point-to-point scanning pattern.

an imaging unit comprising an automated zoom lens to collect light from the subject tissue;

an image display unit for displaying a hyperspectral image; and

a control unit operably connected to the illumination unit, the imaging unit, and the image display unit, the control unit comprising;

a light processing module comprising a CCD camera equipped with a liquid crystal tunable filter and an optical adaptor;

an imaging fiber guide to transport emitted light received by the imaging unit to the light processing module; and

a computer programmed to;

synchronize activities of the illumination unit, the imaging unit, the light processing module, and the image display unit; and

generate the hyperspectral image in about real time.

13. The arrangement of claim 12, further comprising:

an eyewear unit incorporating the illumination unit, the imaging unit, and the image display unit.

14. The arrangement of claim 13, further comprising:

a cylindrical mirror positioned between the eyewear unit and the subject tissue.

15. The arrangement of claim 13, wherein:

the illumination unit is positioned to provide the excitation light at an oblique angle relative to the subject tissue.

16. A method for visual wound assessment on a subject tissue, comprising the steps of:

providing an eyewear unit, an illumination unit, and a control unit;

illuminating a subject tissue with excitation light at multiple wavelengths;

receiving emitted light from the subject tissue;

processing the emitted light to generate a processed hyperspectral image comprising reflectance spectra data for oxy and deoxy hemoglobin; and

displaying the processed hyperspectral image comprising reflectance spectra data for oxy and deoxy hemoglobin in near real time onto a head mounted image display unit.

17. The method of claim 16, wherein,

the illuminating step occurs via a point-to-point scanning pattern.