RESORBABLE MEMBRANE IMPLANTING METHODS FOR REDUCING ADHESIONS

• US 20100114328A1
• Filed: 07/06/2009
• Published: 05/06/2010
• Est. Priority Date: 09/10/2003
• Status: Abandoned Application

• Current Assignee: MAST Biosurgery AG
• Original Assignee: MAST Biosurgery AG
• Inventors: Bluecher, Lukas, Milbocker, Michael T.
• Application Number:
  US12/498,291
• Publication Number:
  US 20100114328A1
• Time in Patent Office: Days
• US Class Current: 623/23.720
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 17/085 with adhesive layer
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable, resorptive for implantable prostheses A61F2210/0004
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00597 Implements comprising a membrane
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2090/0816 for preventing adhesion
• CPC Class Codes: A61F 13/023 wound covering film layers without a fluid retention layer
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body

Abstract

A resorbable thin membrane is applied over a treatment site before a treatment is applied over the resorbable thin membrane to the site. In a particular implementation, a resorbable thin membrane is adhesively applied over a treatment site of tissue before a treatment is conducted onto the tissue whereby the treatment is performed through the resorbable thin membrane. The treatment can be an incision that is made through both the resorbable membrane and into or through the tissue.

Claims

1. A method comprising adhesively applying a resorbable thin membrane over a treatment site of tissue before a treatment is conducted onto the tissue whereby the treatment is performed through the resorbable thin membrane.

2. The method of claim 1 wherein the treatment comprises an incision made through a layer comprising both the resorbable membrane and a membrane of the tissue.

3. The method of claim 2 wherein the resorbable thin membrane is a substantially planar anti-adhesion healing membrane, which is:

(a) substantially-smooth on at least one side;

(b) substantially uniform in composition;

(c) about 10 microns to about 300 microns in thickness;

(d) non-porous;

(e) constructed from a material comprising a resorbable polymer base material selected from one or more of (a) a poly-lactide polymer, (b) a copolymer of lactides, and (c) a poly-lactide polymer and a copolymer of lactides; and

(f) adapted to be resorbed within a period of less than approximately 24 months from an initial implantation of the resorbable thin membrane.

4. The method of claim 2 and further comprising placing a resorbable membrane over the resorbable thin membrane and over the incision.

5. The method of claim 1 and further comprising placing a thin anti-adhesion resorbable membrane over the resorbable thin membrane and over the treatment site following the treatment.

6. The method of claim 1 wherein a thickness of the resorbable thin membrane is between about 100 and 200 microns.

7. The method of claim 1 wherein the resorbable thin membrane is a healing membrane provided in a sterile packaging.

8. The method of claim 7 wherein the step of placing the resorbable thin membrane in a patient is effective to attenuate tissue adhesion.

9. The method of claim 1 further comprising a step of attaching the resorbable thin membrane using stitches, wherein the attaching step comprises lacing a suturing thread through apertures on opposing edges of an opening or gap of the resorbable thin membrane in a manner resembling an arrangement of a shoelace of a shoe, followed by pulling the suturing thread to close the opening or gap.

10. The method of claim 9 further comprising a step of attaching the resorbable thin membrane to a pericardial membrane using stitches.

11. The method of claim 10 wherein the opposing edges have greater thicknesses than other regions of the resorbable thin membrane.

12. The method of claim 11 wherein the attaching step comprises heat bonding the resorbable thin membrane to the pericardial membrane.

13. The method of claim 1 wherein:

the treatment comprises an incision made through a layer comprising both the resorbable membrane and into the tissue; and

the method further comprises a step of attaching the resorbable thin membrane using stitches, the attaching step comprising lacing a suturing thread through opposing edges of an opening or gap of the layer in a manner resembling an arrangement of a shoelace of a shoe, followed by pulling the suturing thread to close the opening or gap.

14. The method of claim 13 wherein the opposing edges have greater thicknesses than other regions of the resorbable thin membrane.

15. The method of claim 13 wherein the attaching step comprises heat bonding the resorbable thin membrane to a pericardial membrane.