Compositions and methods for therapeutic delivery with frozen particles

• US 20100114546A1
• Filed: 10/31/2008
• Published: 05/06/2010
• Est. Priority Date: 10/31/2008
• Status: Active Grant

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Myhrvold, Nathan P., Boyden, Edward S., Wood, Lowell L. JR., Hyde, Roderick A., Sweeney, Elizabeth A., Leuthardt, Eric C.
• Granted Patent: US 8,731,840 B2
• Time in Patent Office: Days
• US Class Current: 703/11
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 5/3015 for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow cell injection devices C12M3/006
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 50/70 for mining of medical data, e.g. analysing previous cases of other patients
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Claims

1. A computer program product, comprising:

a signal bearing medium bearing at least one of

one or more instructions for receiving a first input associated with a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a first subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of predictive regimen parameters from a second subject with one or more similar or dissimilar physical attributes;

one or more instructions for determining from the comparison at least one frozen particle therapeutic composition regimen for the first subject; and

output information.

2. The computer program product of claim 1, wherein the output information is based on the comparison.

3. The computer program product of claim 1, further comprising:

one or more instructions for accessing the first possible dataset in response to the first input.

4. The computer program product of claim 1, further comprising:

one or more instructions for generating the first possible dataset in response to the first input.

5. The computer program product of claim 1, further comprising:

one or more instructions for determining a graphical illustration of the first possible dataset.

6. The computer program product of claim 1, further comprising:

one or more instructions for determining a graphical illustration of the second possible dataset.

7. The computer program product of claim 1, wherein the signal bearing medium includes a computer-readable medium.

8. The computer program product of claim 1, wherein the signal bearing medium includes a recordable medium.

9. The computer program product of claim 1, wherein the signal bearing medium includes a communications medium.

10. A computer program product, comprising:

a signal bearing medium bearing at least one of one or more instructions for processing a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a first subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of predictive regimen parameters from a second subject with one or more similar or dissimilar physical attributes;

one or more instructions for determining from the comparison at least one frozen particle therapeutic composition treatment regimen for the first subject; and

output information.

11. A computer program product, comprising:

a signal bearing medium bearing at least one of

one or more instructions responsive to a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a first subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of predictive regimen parameters for a second subject with one or more similar or dissimilar physical attributes;

one or more instructions for determining from the comparison at least one frozen particle therapeutic composition treatment regimen for the first subject; and

output information.

12. A computer program product, comprising:

a signal bearing medium bearing at least one of

one or more instructions for receiving a first input associated with a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of parameters relating to one or more expected biological changes following administration of one or more frozen particle therapeutic compositions;

one or more instructions for determining from the comparison at least one biological change following administration of one or more frozen particle therapeutic compositions to the subject;

and output information.

13. The computer program product of claim 12, wherein the output information is based on the comparison.

14. The computer program product of claim 12, further comprising:

one or more instructions for accessing the first possible dataset in response to the first input.

15. The computer program product of claim 12, further comprising:

one or more instructions for generating the first possible dataset in response to the first input.

16. The computer program product of claim 12, further comprising:

one or more instructions for determining a graphical illustration of the first possible dataset.

17. The computer program product of claim 12, further comprising:

one or more instructions for determining a graphical illustration of the second possible dataset.

18. The computer program product of claim 12, wherein the signal bearing medium includes a computer-readable medium.

19. The computer program product of claim 12, wherein the signal bearing medium includes a recordable medium.

20. The computer program product of claim 12, wherein the signal bearing medium includes a communications medium.

21. A computer program product, comprising:

a signal bearing medium bearing at least one of one or more instructions for processing a first input associated with a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of parameters relating to one or more expected biological changes following administration of one or more frozen particle therapeutic compositions;

one or more instructions for determining from the comparison at least one biological change following administration of one or more frozen particle therapeutic compositions to the subject; and

output information.

22. A computer program product, comprising:

a signal bearing medium bearing at least one of one or more instructions responsive to a first possible dataset, the first possible dataset including data representative of one or more measurements relating to one or more physical attributes of a subject;

one or more instructions for comparing a value associated with the first possible dataset with a second dataset including values representative of parameters relating to one or more expected biological changes following administration of one or more frozen particle therapeutic compositions;

one or more instructions for determining from the comparison at least one biological change following administration of one or more frozen particle therapeutic compositions to the subject; and

output information.