SUSTAINED RELEASE DRUG DELIVERY DEVICES, METHODS OF USE, AND METHODS OF MANUFACTURING THEREOF
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0 Petitions
Accused Products
Abstract
A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir including the effective agent, an impermeable tube which encloses portions of the reservoir, and a permeable member at an end of the tube.
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Citations
60 Claims
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1-40. -40. (canceled)
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41. A sustained release drug delivery system comprising:
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a drug reservoir comprising a therapeutically effective amount of an agent; an inner tube having first and second open ends and covering at least a portion of said drug reservoir, wherein said inner tube is dimensionally stable and capable of supporting its own weight; and an outer layer, permeable to the passage of said agent, covering only a portion of said inner tube, wherein, upon implantation, agent is released through at least one of the open ends. - View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58)
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59. A sustained release drug delivery system consisting of:
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a drug reservoir comprising a therapeutically effective amount of an agent; an inner tube having first and second open ends and covering at least a portion of said drug reservoir, wherein said inner tube is dimensionally stable and capable of supporting its own weight; an impermeable member at said first open end of the inner tube; and an outer layer, permeable to the passage of said agent, covering only a portion of said inner tube, wherein, upon implantation, agent is released through the second open end.
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60. An injectable sustained release drug delivery system comprising:
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a drug reservoir comprising a therapeutically effective amount of an agent; an inner tube having first and second open ends and covering at least a portion of said drug reservoir, wherein said inner tube is dimensionally stable and capable of supporting its own weight; and an outer layer, permeable to the passage of said agent, covering the first and second open ends but only a portion of said drug reservoir and/or inner tube, wherein, upon implantation, agent is released through at least one of the open ends.
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Specification