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TRANSDERMAL THERAPEUTIC SYSTEM FOR ADMINISTERING THE ACTIVE SUBSTANCE BUPRENORPHINE

  • US 20100119585A1
  • Filed: 11/07/2007
  • Published: 05/13/2010
  • Est. Priority Date: 11/21/2006
  • Status: Active Grant
First Claim
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1. Transdermal therapeutic system for administering buprenorphine to the skin, comprising an active-ingredient-impermeable backing layer, at least one pressure-sensitive adhesive matrix layer comprising the active ingredient buprenorphine and at least one carboxylic acid, and, if desired, a protective layer to be detached before use, characterized in that the matrix layer is constructed on the basis of polysiloxanes or polyisobutylene, the buprenorphine is in solution in the carboxylic acid or carboxylic acids, and this solution is in dispersion in the form of droplets in the matrix layer.

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