MULTI-COMPONENT PHARMACEUTICAL DOSAGE FORM
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0 Petitions
Accused Products
Abstract
A multi-component pharmaceutical dosage form comprising a plurality of drug substance—containing sub-units, being capsule compartments and/or solid sub-units comprising a solid matrix of a polymer which contains a drug substance, the sub-units being connected together in the assembled dosage form by a weld between parts of the assembled dosage form.
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Citations
75 Claims
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1. to 37. (canceled)
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38. A multi-component dosage form comprising:
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a plurality of sub-units disposed in end-to-end relationship, each of the plurality of sub-units selected from a group consisting of (i) capsule compartment sub-units respectively comprising at least one cavity formed therein and being configured to release a drug-substance contained within the at least one cavity into a gastro-intestinal environment and (ii) solid sub-units comprising a matrix of a polymer; a first joint formed between a first sub-unit of the plurality of sub-units and a second sub-unit of the plurality of sub-units, the first joint comprising a plug formed as a unitary part of the first sub-unit and a socket formed as a unitary part of the second sub-unit; and a second joint formed between the second sub-unit and a third sub-unit of the plurality of sub-units, the second joint comprising a plug formed as a unitary part of the second sub-unit and a socket formed as a unitary part of the third sub-unit. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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52. A multi-component dosage form comprising:
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a plurality of sub-units disposed in end-to-end relationship, each of the plurality of sub-units selected from a group consisting of (i) capsule compartment sub-units respectively comprising at least one cavity formed therein and being configured to release a drug-substance contained within the at least one cavity into a gastro-intestinal environment and (ii) solid sub-units respectively comprising a matrix of a polymer; a first joint formed between a first sub-unit of the plurality of sub-units and a second sub-unit of the plurality of sub-units, the first joint comprising a first socket formed as a unitary part of the first sub-unit and a first plug formed as a unitary part of the second sub-unit; and a second joint formed between the second sub-unit and a third sub-unit of the plurality of sub-units, the second joint comprising a second plug formed as a unitary part of the second sub-unit and a second socket formed as a unitary part of the third sub-unit; wherein the second sub-unit includes a first section having a closed end and an open end, a second section having a closed end and an open end, and a sub-unit joint formed between the first and second sections of the second sub-unit adjacent the respective open ends. - View Dependent Claims (53, 54, 55, 56, 57, 58, 59, 60)
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61. A multi-component dosage form comprising:
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first and second sub-units disposed in end-to-end relationship along a line that defines an axial direction, the first and second sub-units selected from a group consisting of (i) capsule compartment sub-units respectively comprising at least one cavity formed therein and being configured to release a drug-substance contained within the at least one cavity into a gastro-intestinal environment and (ii) solid sub-units comprising a matrix of a polymer; and a first joint formed between the first and second sub-units comprising a first plug formed as a unitary part of the first sub-unit and a first socket formed as a unitary part of the second sub-unit; wherein the first sub-unit includes an outer wall having an outer diameter that is radially larger than an outer diameter of the first plug and the second sub-unit includes an outer wall having an outer diameter that is radially larger than an outer diameter of the first socket; and wherein the first joint interconnects the first and second sub-units together such that the relative axial position between the first and second sub-units is solely deliminated by engaging outer wall axial end parts of the respective first and second sub-units. - View Dependent Claims (62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75)
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Specification