EXPANDABLE BRACHYTHERAPY DEVICE

• US 20100121129A1
• Filed: 01/22/2010
• Published: 05/13/2010
• Est. Priority Date: 11/05/2004
• Status: Active Grant

• Current Assignee: Theragenics Corporation (Juniper Investment Co. LLC)
• Original Assignee: Theragenics Corporation (Juniper Investment Co. LLC)
• Inventors: GOVIL, AMIT PRAKASH, WHITE, JACK C., GRIFFITH, NATHAN CHRISTOPHER, STEPHENS, DAVID WESLEY, BERGMAN, JOSHUA J., MILLAGE, KYLE KEVIN
• Granted Patent: US 8,398,534 B2
• Time in Patent Office: Days
• US Class Current: 600/7
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: A61N 2005/1008 Apparatus for temporary insertion of sources, e.g. afterloaders
• CPC Class Codes: A61N 2005/1018 with multiple channels for guiding radioactive sources
• CPC Class Codes: A61N 2005/1024 Seeds
• CPC Class Codes: A61N 5/1007 Arrangements or means for the introduction of sources into the body
• CPC Class Codes: A61N 5/1015 Treatment of resected cavities created by surgery, e.g. lumpectomy

Abstract

A brachytherapy device including an elongate member comprising a proximal portion and a distal portion. The device also includes a movable surface portion surrounding at least the distal portion of the elongate member and a plurality of source lumen tubes defining respective source lumens, the source lumen tubes being located around the elongate member, distal ends of the source lumen tubes coupled to the distal portion of the elongate member, the source lumen tubes extending a sufficient distance in a proximal direction such that the source lumen tubes extend outside a body when distal portions of the source lumen tubes are positioned in a body cavity for brachytherapy. The device also has structure coupled to the distal ends of the source lumen tubes for positioning the distal portions of the source lumen tubes at different distances from the elongate member for brachytherapy by exerting a force in a proximal direction on the distal ends of the source lumen tubes, the structure including an actuator for actuating the structure, at least a portion of the actuator being located outside the body when the distal portions of the source lumen tubes are positioned in a body cavity for brachytherapy. The device also includes a ring, tube or manifold securing a portion of the source lumen tubes proximal to the distal portion around the elongate member and a source of radiation suitable for insertion into the source lumens.

Claims

1. A brachytherapy device comprising:

an elongate member comprising a proximal portion and a distal portion;

a movable surface portion surrounding at least the distal portion of the elongate member;

a plurality of source lumen tubes defining respective source lumens, said source lumen tubes being located around the elongate member, distal ends of the source lumen tubes coupled to the distal portion of the elongate member, the source lumen tubes extending a sufficient distance in a proximal direction such that said source lumen tubes extend outside a body when distal portions of said source lumen tubes are positioned in a body cavity for brachytherapy;

structure coupled to the distal ends of said source lumen tubes for positioning said distal portions of said source lumen tubes at different distances from the elongate member for brachytherapy by exerting a force in a proximal direction on the distal ends of said source lumen tubes, said structure including an actuator for actuating said structure, at least a portion of said actuator being located outside the body when said distal portions of said source lumen tubes are positioned in a body cavity for brachytherapy;

a ring, tube or manifold securing a portion of said source lumen tubes proximal to said distal portion around said elongate member; and

a source of radiation suitable for insertion into the source lumens.

2. The brachytherapy device of claim 1, wherein the plurality of source lumen tubes comprise at least two source lumens.

3. The brachytherapy device of claim 1, wherein the plurality of source lumen tubes comprise at least four source lumens.

4. The brachytherapy device of claim 1, wherein the elongate member comprises an internal lumen into which a radiation source may be inserted for providing brachytherapy treatment.

5. The brachytherapy device of claim 1, wherein said movable surface portion is formed by an inflatable balloon

6. The brachytherapy device of claim 5, wherein said inflatable balloon comprises an inflation lumen.

7. The brachytherapy device of claim 1, wherein said movable surface portion is movable relative to said source lumen tubes.

8. The brachytherapy device of claim 1, wherein said movable surface portion acts as a barrier between the source lumen tubes and body tissue.

9. The brachytherapy device of claim 1, wherein the movable surface portion comprises elastic material.

10. The brachytherapy device of claim 1, further comprising a coating on at least one outer surface of said device in order to reduce adhesion to body tissue.

11. A brachytherapy device comprising:

an elongate member comprising a proximal portion and a distal portion;

a plurality of source lumen tubes defining respective source lumens, said source lumen tubes being located around the elongate member, distal ends of the source lumen tubes coupled to the distal portion of the elongate member, the source lumen tubes extending a sufficient distance in a proximal direction such that said source lumen tubes extend outside a body when distal portions of said source lumen tubes are positioned in a body cavity for brachytherapy;

an actuator associated with the elongate member for positioning said distal portions of said source lumen tubes at different distances from the elongate member for brachytherapy, at least a portion of said actuator being located outside the body when said distal portions of said source lumen tubes are positioned in a body cavity for brachytherapy;

a ring, tube or manifold securing a portion of said source lumen tubes proximal to said distal portion around said elongate member, said ring, tube or manifold being movable relative to said elongate member;

a source of radiation suitable for insertion into the source lumens; and

an outer sheath around a distal portion of the device.

12. The brachytherapy device of claim 11, wherein the outer sheath is formed integrally with an element of the device.

13. The brachytherapy device of claim 11, wherein the outer sheath comprises a material that is suitable for reducing a dose gradient in a treatment area.

14. The brachytherapy device of claim 11, wherein the plurality of source lumen tubes comprise at least two source lumens.

15. The brachytherapy device of claim 11, wherein the plurality of source lumen tubes comprise at least four source lumens.

16. The brachytherapy device of claim 11, wherein the elongate member comprises an internal lumen into which a radiation source may be inserted for providing brachytherapy treatment.

17. The brachytherapy device of claim 11, wherein the outer sheath comprises elastic material.

18. The brachytherapy device of claim 11, wherein said outer sheath acts as a barrier between the source lumen tubes and body tissue.

19. The brachytherapy device of claim 11, further comprising a coating on at least one outer surface of said device in order to reduce adhesion to body tissue.

20. A device for use in brachytherapy comprising:

a proximal portion;

a plurality of source lumen tubes comprising distal ends coupled together and proximal ends, a distal portion of the source lumen tubes defining an expandable structure adjacent the distal ends thereof, the source lumen tubes defining source lumens that extend from the proximal ends of the source lumen tubes into the distal portion of the source lumen tubes for receiving a source of radiation therein;

an inner tube extending from the proximal portion to the distal ends of the source lumen tubes, the inner tube defining a source lumen for receiving a source of radiation therein;

a ring, tube or manifold securing a portion of said source lumen tubes proximal to said distal portion around said inner tube;

an actuator operatively associated with the source lumen tubes for reducing a distance between the distal ends of the source lumen tubes and the ring, tube or manifold to direct the expandable structure from a first contracted position to a second expanded position; and

a source of radiation suitable for insertion into the source lumens.

21. The brachytherapy device of claim 20, wherein the plurality of source lumen tubes comprise at least two source lumens.

22. The brachytherapy device of claim 20, wherein the plurality of source lumen tubes comprise at least four source lumens.

23. The brachytherapy device of claim 20, wherein said ring, tube or manifold is movable relative to said inner tube.

24. The brachytherapy device of claim 20, further comprising an outer sheath around the distal portion of the source lumen tubes.

25. The brachytherapy device of claim 24, wherein the outer sheath is formed integrally with an element of the device.

26. The brachytherapy device of claim 20, further comprising a coating on at least one outer surface of said device in order to reduce adhesion to body tissue.

27. The brachytherapy device of claim 20, further comprising an outer sheath comprising a material suitable to reduce a dose gradient in a treatment area.

28. The device of claim 20, wherein a proximal portion of each source lumen tube extends a sufficient distance such that a proximal portion of each source lumen tube is located outside a body when the device is positioned for brachytherapy in a body cavity.