DEVICES AND METHODS FOR DELIVERING THERAPEUTIC SUBSTANCES FOR THE TREATMENT OF SINUSITIS AND OTHER DISORDERS
First Claim
1. A method for delivering a substance into a paranasal sinus of a subject, the method comprising:
- advancing an expandable reservoir, in an unexpanded configuration, into a paranasal sinus of the subject, the reservoir being coupled with a reservoir filling tube having a lumen through which the substance is introduced into the reservoir, the reservoir having a barrier that controls the rate at which the substance passes out of the reservoir;
introducing a substance through the lumen of the reservoir filling tube and into the reservoir, thereby causing the reservoir to fill and expand;
detaching the reservoir filling tube from the reservoir; and
removing the reservoir filling tube from the subject, thus leaving the reservoir behind such that the substance will pass out of the reservoir through the barrier of the expandable reservoir at a predetermined rate.
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Accused Products
Abstract
Devices and methods for delivering drugs and other therapeutic or diagnostic substances to desired locations within the bodies of human or non-human animal subjects. An implantable delivery device comprising a reservoir is initially attached to a deliver catheter or delivery tool and is introduced into the body and positioned at a desired site. A therapeutic or diagnostic substance is then introduced into the reservoir and the delivery catheter or deliver tool is then removed, leaving the implantable delivery device implanted within the body. The substance is then delivered from the reservoir at a rate that causes the desire diagnostic or therapeutic effect. Also provided are substance eluting stents that elute substance from a selected surface of the stent (e.g., the outer surface) but not from another surface of the stent (e.g., the inner surface).
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Citations
23 Claims
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1. A method for delivering a substance into a paranasal sinus of a subject, the method comprising:
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advancing an expandable reservoir, in an unexpanded configuration, into a paranasal sinus of the subject, the reservoir being coupled with a reservoir filling tube having a lumen through which the substance is introduced into the reservoir, the reservoir having a barrier that controls the rate at which the substance passes out of the reservoir; introducing a substance through the lumen of the reservoir filling tube and into the reservoir, thereby causing the reservoir to fill and expand; detaching the reservoir filling tube from the reservoir; and removing the reservoir filling tube from the subject, thus leaving the reservoir behind such that the substance will pass out of the reservoir through the barrier of the expandable reservoir at a predetermined rate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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13. The method of claim 13, wherein the closure mechanism comprises a one-way valve.
Specification