Closed-Loop Clot Lysis
First Claim
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1. A system for delivering acoustic energy to a clot within a blood vessel, the system comprising:
- a. a focused-ultrasound phased-array transducer;
b. means for monitoring blood flow in a vicinity of the blood vessel as ultrasound energy is directed at the blood vessel; and
c. a controller for operating the transducer and adjusting transducer operation based on the monitored blood flow.
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Abstract
The present invention provides procedures and systems that use a closed-loop approach for directing ultrasound energy at a clot while monitoring blood flow and/or liquification of the clot tissue so as to allow automated and/or manual adjustments to various treatment parameters.
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Citations
33 Claims
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1. A system for delivering acoustic energy to a clot within a blood vessel, the system comprising:
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a. a focused-ultrasound phased-array transducer; b. means for monitoring blood flow in a vicinity of the blood vessel as ultrasound energy is directed at the blood vessel; and c. a controller for operating the transducer and adjusting transducer operation based on the monitored blood flow. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 19)
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17. A system for delivering acoustic energy to a clot within a blood vessel, the system comprising:
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a. a focused-ultrasound phased-array transducer; b. means for monitoring liquid content of the clot as ultrasound energy is directed at the clot; and c. a controller for operating the transducer and adjusting transducer operation based on the monitored liquid content. - View Dependent Claims (18)
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20. A method for treating a clot within a blood vessel, the method comprising the steps of:
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a. applying focused ultrasound energy to the blood vessel using a focused-ultrasound phased-array transducer; b. monitoring blood flow in a vicinity of the blood vessel as ultrasound energy is directed at the blood vessel; and c. operating the transducer including adjusting transducer operation based on the monitored blood flow. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method for treating a clot within a blood vessel, the method comprising the steps of:
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a. applying focused ultrasound energy to the clot using a focused-ultrasound phased-array transducer; b. monitoring liquid content of the clot as ultrasound energy is directed at the blood vessel; and c. operating the transducer including adjusting transducer operation based on the monitored liquid content. - View Dependent Claims (32, 33)
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Specification