Atrial Capture Test for An Active Implantable Medical Device

• US 20100125309A1
• Filed: 11/18/2009
• Published: 05/20/2010
• Est. Priority Date: 11/19/2008
• Status: Active Grant

• Current Assignee: Sorin CRM USA (MicroPort Scientific Corp.)
• Original Assignee: Sorin CRM SAS
• Inventors: CASSET, Cyrille
• Granted Patent: US 8,214,036 B2
• Time in Patent Office: Days
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

An active implantable medical device that is able to perform an atrial capture test. The device includes circuits for delivering atrial stimulation pulses, and testing atrial capture, namely to detect the occurrence of an atrial contraction after the application of an atrial stimulation pulse. An acceleration sensor is used to deliver an EA signal representative of the movements produced by the contractions of the atrial cavity. The EA signal is analyzed to recognize and isolate in this EA signal a component EA4 corresponding to the fourth endocardiac acceleration peak (PEA4) associated with the atrial activity. The presence or absence of this component EA4 is used to define the atrial capture or loss of capture. The signal analysis preferably quantifies an EA parameter (T, T+D), such as the energy of the EA signal within analysis time windows, each having duration D, of successive analysis (W1 . . . Wn) triggered after the atrial stimulation (P) and ending before a ventricular detection or stimulation.

Claims

1. An active implantable medical device of the cardiac pacemaker, resynchronization, cardioversion and/or defibrillation type, comprising:

means for producing low energy atrial stimulation pulses (P) to be applied to an electrode implanted on the atrial cavity of a patient; and

means for detecting an occurrence of an atrial contraction after the application of an atrial stimulation pulse P, said means comprising;

an acceleration sensor having an endocardiac acceleration output (EA) signal representative of movements produced by the contractions of the atrial cavity;

means for analyzing the EA signal to recognize and isolate in the EA signal an EA4 component corresponding to a fourth peak of endocardiac acceleration associated to the atrial activity, including means for determining the presence or absence of said EA4 component, the presence of said EA4 component being representative of an atrial capture and the absence of said EA4 component being representative of an atrial loss of capture; and

means for quantifying a parameter of the EA signal within at least one analysis time window, wherein the at least one analysis time window is triggered to begin at or after the moment of application of the atrial stimulation pulse (P), and terminate before a second specific event, and the quantified parameter is representative of energy of the EA signal over the duration of the at least one analysis time window.

2. The device of claim 1 wherein the at least one analysis time window has a fixed duration and the quantified parameter is the energy of the EA signal integrated over said fixed duration.

3. The device of claim 1, wherein the said second specific event is an event selected from among the group consisting of a ventricular detection, a ventricular stimulation, an appearance of an EA1 signal, and a fixed delay period.

4. The device of claim 3, wherein the at least one analysis time window further comprise a plurality of analysis time windows (W1 . . . Wn) successively shifted in time wherein the means for quantifying the EA signal parameter further comprises means for qualifying a parameter I(T, T+D) for at least a first subset of said plurality of successive analysis windows.

5. The device of claim 4, wherein the plurality of successive analysis windows (W1 . . . Wn) are overlapping in time.

6. The device of claim 1, wherein the means for analyzing the EA signal further comprises means for comparing the parameter of the EA signal quantified in the time window (Wi) to a given threshold (S).

7. The device of claim 6, wherein the threshold S is a threshold selected from among the group consisting of a fixed threshold;

a parameterizable threshold;

an adaptive threshold recalculated at regular intervals;

an adaptive threshold that recalculated on each cycle having a valid atrial event.

8. The device of claim 1, further comprising means for searching an atrial capture threshold, including means for changing in an iterative way the low energy of the produced atrial stimulation pulse, and means for testing for an atrial capture or loss of capture in response to said changing low energy atrial stimulation pulses.

9. The device of claim 1, wherein the acceleration sensor is selected from among the group consisting of an endocardial sensor;

an epicardial sensor; and

an external sensor.