SYSTEM AND METHOD FOR MODULATING ACTION POTENTIAL PROPAGATION DURING SPINAL CORD STIMULATION
First Claim
1. A method of providing therapy to a patient, comprising:
- conveying an electrical pulsed waveform between at least one caudal electrode and spinal cord tissue, thereby evoking action potentials that are orthodromically propagated along dorsal column (DC) neural fibers and evoking action potentials that are antidromically propagated along the DC neural fibers; and
conveying electrical energy between at least one rostral electrode and the spinal cord tissue, thereby modulating times that the action potentials orthodromically propagated along the DC neural fibers arrive at the brain of the patient.
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Abstract
A method and neurostimulator for providing therapy to a patient is provided. In one technique, an electrical pulsed waveform is conveyed between a caudal electrode and spinal cord tissue, thereby evoking action potentials that are orthodromically propagated along dorsal column fibers and evoking action potentials that are antidromically propagated along the DC fibers. Electrical energy is conveyed between a rostral electrode and the spinal cord tissue, thereby modulating times that the action potentials orthodromically propagated along the DC fibers arrive at the brain. In another technique, an electrical pulsed waveform is conveyed through a first electrode, thereby evoking action potentials that are propagated along a neural axon, and electrical energy is conveyed through the second electrode. The electrical energy has a frequency that is greater than a pulse rate of the electrical pulsed waveform, such that the action potentials propagated along the neural axon are blocked by the electrical energy.
217 Citations
30 Claims
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1. A method of providing therapy to a patient, comprising:
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conveying an electrical pulsed waveform between at least one caudal electrode and spinal cord tissue, thereby evoking action potentials that are orthodromically propagated along dorsal column (DC) neural fibers and evoking action potentials that are antidromically propagated along the DC neural fibers; and conveying electrical energy between at least one rostral electrode and the spinal cord tissue, thereby modulating times that the action potentials orthodromically propagated along the DC neural fibers arrive at the brain of the patient. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of providing therapy to a patient using first and second electrodes spaced along a first neural axon of the patient, comprising:
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conveying an electrical pulsed waveform through the first electrode, thereby evoking action potentials that are propagated along the first neural axon; and conveying electrical energy through the second electrode, wherein the electrical energy has a frequency that is greater than a pulse rate of the electrical pulsed waveform, such that the action potentials propagated along the first neural axon are blocked by the electrical energy. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A neurostimulator, comprising:
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a plurality of electrical terminals configured for being electrically coupled to at least one electrode carrying stimulation lead; and analog output circuitry configured for conveying an electrical pulsed waveform to or from a first one of the electrical terminals, and for simultaneously conveying electrical energy to or from a second one of the electrical terminals in accordance with a set of stimulation parameters, wherein the electrical energy has a frequency that is greater than a pulse rate of the electrical pulsed waveform; and control circuitry configured for generating the set of stimulation parameters. - View Dependent Claims (25, 26, 27, 28, 29, 30)
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Specification