NON-INVASIVE RECOVERY OF RNA AND ANALYSIS OF GENE EXPRESSION IN SKIN
First Claim
Patent Images
1. A method for isolating RNA molecules from a skin sample comprising:
- (a) applying a liquid to a skin surface;
(b) applying a substrate to said liquid;
(c) allowing said liquid to harden;
(d) removing said substrate;
(e) removing said skin sample from said liquid; and
(f) isolating RNA from said skin sample.
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Accused Products
Abstract
A liquid is placed on an area of skin in which an RNA sample is to be extracted. The liquid is configured to harden which allows for the hardened material to be peeled off. In some implementations, a substrate is attached to the liquid before it hardens to facilitate removal of the skin sample.
15 Citations
20 Claims
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1. A method for isolating RNA molecules from a skin sample comprising:
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(a) applying a liquid to a skin surface; (b) applying a substrate to said liquid; (c) allowing said liquid to harden; (d) removing said substrate; (e) removing said skin sample from said liquid; and (f) isolating RNA from said skin sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 17, 19)
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11. A method for isolating RNA molecules from a skin sample comprising:
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(a) applying a liquid to a skin surface; (b) allowing said liquid to harden; (d) removing said liquid; (e) removing said skin sample from said liquid; and (f) isolating RNA from said skin sample. - View Dependent Claims (12, 13, 14, 15, 16, 18)
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20. A kit for isolating RNA molecules from a skin sample comprising:
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(a) a liquid; (b) a substrate; (c) a cell lysis buffer suitable of preserving RNA; and (d) instructions.
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Specification