STEROID MODULATORS OF PROGESTERONE RECEPTOR AND/OR GLUCOCORTICOID RECEPTOR
First Claim
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1. A compound of structural Formula I or a salt thereof, wherein:
- R1-R32 are independently selected from the group consisting of hydrogen and deuterium;
R33 is selected from the group consisting of —
CH3, —
CH2D, —
CHD2, and —
CD3; and
at least one of R1-R33 is deuterium or contains deuterium.
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Abstract
The present invention relates to new steroid modulators of progesterone receptor activity and/or glucocorticoid receptor activity, pharmaceutical compositions thereof, and methods of use thereof.
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Citations
48 Claims
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1. A compound of structural Formula I
or a salt thereof, wherein: -
R1-R32 are independently selected from the group consisting of hydrogen and deuterium; R33 is selected from the group consisting of —
CH3, —
CH2D, —
CHD2, and —
CD3; andat least one of R1-R33 is deuterium or contains deuterium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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Specification