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METHOD OF DIFFERENTIATING MAMMALIAN PROGENITOR CELLS INTO INSULIN PRODUCING PANCREATIC ISLET CELLS

  • US 20100136688A1
  • Filed: 05/21/2009
  • Published: 06/03/2010
  • Est. Priority Date: 05/22/2008
  • Status: Active Grant
First Claim
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1. A method for differentiating progenitor cells into insulin-producing pancreatic cells, comprising:

  • (a) incubating the progenitor cells in serum-free pre-induction media comprising sodium butyrate; and

    , subsequently,(b) incubating the progenitor cell in induction media comprising knock-out replacement serum;

    for a time sufficient to differentiate the progenitor cells into insulin producing pancreatic cells.

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