TECHNIQUES FOR EVALUATING STRESS URINARY INCONTINENCE (SUI) USING INVOLUNTARY REFLEX COUGH TEST

• US 20100137737A1
• Filed: 12/21/2009
• Published: 06/03/2010
• Est. Priority Date: 10/18/2005
• Status: Active Grant

• Current Assignee: Pneumoflex Systems, LLC
• Original Assignee: Pneumoflex Systems, LLC
• Inventors: Miller, Stuart P., Phelipa, Michael M., Briganti, Mary W., Stephens, Robert E., Addington, W. Robert
• Granted Patent: US 8,602,987 B2
• Time in Patent Office: Days
• US Class Current: 600/546
• CPC Class Codes: A61B 5/0823 Detecting or evaluating cough events
• CPC Class Codes: A61B 5/202 Assessing bladder functions, e.g. incontinence assessment
• CPC Class Codes: A61B 5/205 Determining bladder or urethral pressure
• CPC Class Codes: A61B 5/391 of genito-urinary organs
• CPC Class Codes: A61B 5/4047 afferent nerves, i.e. nerves that relay impulses to the central nervous system
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A system and method evaluates a patient for stress urinary incontinence. An involuntary reflex cough event is induced within the patient that activates the nucleus ambiguous and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient. And elecromyogram (EMG) is obtained from the involuntary cough activated paraspinal muscles and its duration determined. Any urine leakage time that occurs during the involuntary reflex cough event is identified and correlated within a processor together with the urine leakage time and EMG and duration of cough event to determine stress urinary incontinence.

Claims

1. A method of evaluating a patient for stress urinary incontinence, comprising:

inducing an involuntary reflex cough event within the patient that activates the nucleus ambiguous and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient;

obtaining an electromyogram (EMG) from the involuntary cough activated paraspinal muscles while inducing the involuntary reflex cough event and determining its duration;

identifying any urine leakage time that occurs during the involuntary reflex cough event and correlating within a processor the urine leakage time with the EMG and duration of the cough event to determine stress urinary incontinence.

2. The method according to claim 1 and further comprising obtaining the EMG from the L5/S1 paraspinal muscles.

3. The method according to claim 1 and further comprising having the patient produce a voluntary cough before inducing an involuntary cough.

4. The method according to claim 3 and further comprising obtaining an EMG and identifying any urine leakage time during the voluntary cough and correlating any urine leakage time with the urine leakage time obtained during the involuntary reflex cough event.

5. The method according to claim 1 and further comprising determining the intra-abdominal pressure (IAP) during the involuntary reflex cough event and correlating the TAP with the duration of the involuntary reflex cough event and urine leakage time.

6. The method according to claim 5 and further comprising determining the peak IAP and correlating it with the IAP and duration of the involuntary reflex cough event.

7. The method according to claim 6 and further comprising determining average IAP and correlating it with the peak IAP and duration of the involuntary reflex cough event.

8. The method according to claim 7 and further comprising determining an area under the curve corresponding to IAP samples obtained during the involuntary reflex cough event and correlating it with the IAP and duration of the involuntary reflex cough event.

9. A method of evaluating a patient for stress urinary incontinence, comprising:

having the patient produce a voluntary cough and identifying any urine leakage time during the voluntary cough;

inducing an involuntary reflex cough event within the patient that activates the nucleus ambiguous and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient; and

identifying any urine leakage time that occurs during the involuntary reflex cough event and correlating within a processor the urine leakage time for both the voluntary cough and involuntary cough event and their duration to determine stress urinary incontinence.

10. The method according to claim 9 and further comprising determining the intra-abdominal pressure (IAP) during the voluntary cough and involuntary reflex cough event and correlating the IAP with the duration of the involuntary reflex cough event and urine leakage time.

11. The method according to claim 10 and further comprising determining the peak IAP and correlating it with the IAP.

12. The method according to claim 11 and further comprising determining average IAP and correlating it with the peak IAP.

13. The method according to claim 12 and further comprising determining an area under the curve corresponding to IAP samples.

14. The method according to claim 9 and further comprising obtaining an electromyogram (EMG) from the involuntary cough activated paraspinal muscles while inducing the involuntary reflex cough event and determining the cough event duration and correlating the EMG with the duration of the cough event and urine leakage time.

15. The method according to claim 14 and further comprising obtaining the EMG from the L5/S1 paraspinal muscles.

16. A system for evaluating a patient for stress urinary incontinence, comprising:

a nebulizer containing an agent that induces an involuntary reflex cough event within the patient that activates the nucleus ambiguous and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient;

at least one electromyogram (EMG) pad configured to be attached to the lumbar region of the patient'"'"'s back and obtain EMG signals from the involuntary cough activated paraspinal muscles;

a urine leak detect device configured to detect urine leakage; and

a processing device that receives the EMG and correlates the EMG and duration of the involuntary reflex cough event with an urine leakage time to determine stress urinary incontinence.

17. The system according to claim 16 wherein said processing device comprises a portable handheld device comprising,

a housing configured for handheld use;

at least one interface carried by the housing and configured to receive the EMG and data related to urine leakage time; and

a processor carried by the housing and configured to correlate the EMG and duration of the involuntary reflex cough event and urine leakage time to determine stress urinary incontinence.

18. The system according to claim 16 wherein said at least one EMG pad is configured to obtain the EMG from the L5/S1 paraspinal muscles.

19. The system according to claim 16 a further comprising a catheter configured to fill the bladder with a fluid and measure the intra-abdominal pressure (IAP) during the involuntary reflex cough event.

20. The system according to claim 19 wherein said processing device is configured to determine the peak IAP and correlate it with the IAP and duration of the involuntary reflex cough event.

21. The system according to claim 20 wherein said processing device is configured to determine average IAP and correlate it with the peak IAP and duration of the involuntary reflex cough event.

22. The system according to claim 21 wherein said processing device is configured to calculate an area under the curve corresponding to IAP samples obtained during the involuntary reflex cough event and correlate it with the IAP and duration of the involuntary reflex cough event.

23. A device for evaluating a patient for stress urinary incontinence, comprising:

a housing configured for handheld use;

at least one interface carried by the housing and configured to receive an electromyogram (EMG) data from paraspinal muscles in the pelvis of the patient that had been activated by an involuntary reflex cough event that activates the nucleus ambiguous and medial motor cell column of the patient and data relating to an urine leakage time during the involuntary reflex cough test; and

a processor carried by the housing and configured to receive and process the EMG and urine leakage time and correlate data regarding the duration of the involuntary reflex cough event to determine stress urinary incontinence.

24. The device according to claim 23 wherein said at least one interface is configured to receive pressure readings regarding intra-abdominal pressure (IAP) obtained during the involuntary cough reflex test, and said processor is configured to correlate the IAP with the EMG and urine leakage time and duration of the cough event to determine stress urinary incontinence.

25. The device according to claim 24 wherein said processor is configured to determine average IAP and correlate it with the peak IAP and duration of the involuntary cough reflex event.

26. The device according to claim 25 wherein said processor is configured to determine average IAP and correlate it with the peak IAP and duration of the involuntary reflex cough event.

27. The device according to claim 26 wherein said processor is configured to calculate an area under the curve corresponding to IAP samples obtained during the involuntary reflex cough event and correlate it with the IAP and duration of the involuntary reflex cough event.