DEVICE FOR INFUSION OF AT LEAST TWO MEDICAMENTS

• US 20100137828A1
• Filed: 02/29/2008
• Published: 06/03/2010
• Est. Priority Date: 03/02/2007
• Status: Active Grant

• Current Assignee: Philips Medizin Systeme Boblingen GmbH (Koninklijke Philips N.V.)
• Original Assignee: Up Management GmbH
• Inventors: Knoll, Reinhold, Pfeiffer, Ulrich, Michard, Frederic
• Granted Patent: US 8,608,683 B2
• Time in Patent Office: Days
• US Class Current: 604/503
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A device for infusing of at least one medicament includes at least two actuators configured to cause at least two medicaments to be infused; at least one sensor configured to measure a value of at least two parameters; and a controller configured to control the at least two actuators, wherein the controller is programmed to activate the at least two actuators depending on the values of each of the at least two parameters, and wherein the controller is arranged so as to consider a dependency of the at least two medicaments.

Claims

1-8. -8. (canceled)

9. A device for infusing of at least one medicament comprising:

at least two actuators configured to cause at least two medicaments to be infused;

at least one sensor configured to measure a value of at least two parameters; and

a controller configured to control the at least two actuators, wherein the controller is programmed to activate the at least two actuators depending on the values of each of the at least two parameters, and wherein the controller is arranged so as to consider a dependency of the at least two medicaments.

10. A device as recited in claim 9, wherein the at least two parameters are selected from the group consisting of:

a systolic arterial pressure (SAP), a mean arterial pressure (MAP), a pulse oximetry plethysmographic waveform variation (POPV), a hemoglobin (Hb), a hematocrit (het), a heart rate (FIR), a pulse pressure variation (PPV), a systolic pressure variation (SPV), a pre-ejection period variation (PEPV) and a central venous blood oxygen saturation (ScVO2).

11. A device as recited in claim 9, wherein the at least one medicament is selected from the group consisting of:

a fluid, red blood cells, vasoactive agents and positively inotropic acting agents.

12. A device as recited in claim 9, wherein the controller includes a maximum device having a maxima memory containing a value for a maximum dose of the at least two medicaments, a dose determining device configured to determine a dose of the at least two medicaments and a maximum stopper configured to stop the infusion of the at least two medicaments when the maximum dose is reached.

13. A device as recited in claim 9, wherein the controller includes an effect controlling device having an effect memory configured to store a list of the at least two medicaments and corresponding expected parameter changes, and wherein the controller further includes a stopper configured to stop the infusion of a medicament, wherein the effect controlling device is programmed to activate the stopper if the at least two medicaments are infused and at least one corresponding expected parameter change does not occur.

14. The device as recited in claim 9, wherein the controller includes a distance analyzer configured to determine a distance between a threshold value and a parameter position, wherein the parameter position is defined by the values of the at least two parameters, and wherein the controller further includes a converting unit configured to convert the distance into a dose of one of the at least two medicaments, and wherein the controller is programmed to activate the at least one actuator according to the dose.

15. The device as recited in claim 9, wherein the controller is a closed loop controller.

16. A method for infusing of at least one medicament comprising:

measuring at least two parameters; and

causing at least two medicaments to be infused based on a value of each of the at least two parameters, and at least one dependency between the at least two medicaments.