METHOD AND APPARATUS FOR DETERMINING RELATIVE POSITIONING BETWEEN NEUROSTIMULATION LEADS

• US 20100137944A1
• Filed: 11/23/2009
• Published: 06/03/2010
• Est. Priority Date: 12/03/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Zhu, Changfang
• Granted Patent: US 8,380,301 B2
• Time in Patent Office: Days
• US Class Current: 607/59
• CPC Class Codes: A61B 5/06 Devices, other than using radiation, for detecting or locating foreign bodies for removing same A61B17/50 ; determining position of probes within or on the body of the patient
• CPC Class Codes: A61B 5/063 using impedance measurements
• CPC Class Codes: A61B 5/407 Evaluating the spinal cord A61B5/4896 takes precedence
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

A method and medical system for operating two leads disposed adjacent tissue of a patient are provided. A first one of a pair of electrodes respectively carried by the two leads is activated to generate an electrical field within the tissue. An electrical parameter in response to the generated electrical field is measured at a second one of the pair of electrodes. A reference electrical parameter is measured in response to the generated electrical field at a reference electrode carried by the same one of the two leads that carries the first electrode. A reference distance between the first electrode and the reference electrode is known prior to the generation of the electrical field. The ratio between the measured electrical parameter and the measured reference electrical parameter is computed, and the distance between the pair of electrodes is computed as a function of the computed ratio and the reference distance.

Claims

1. A method of operating two leads disposed adjacent tissue of a patient, the method comprising:

activating a first one of a pair of electrodes respectively carried by the two leads to generate an electrical field within the tissue;

measuring an electrical parameter in response to the generated electrical field at a second one of the pair of electrodes;

measuring a reference electrical parameter in response to the generated electrical field at a reference electrode carried by the same one of the two leads that carries the first electrode, wherein a reference distance between the first electrode and the reference electrode is known prior to the generation of the electrical field;

computing a ratio between the measured electrical parameter and the measured reference electrical parameter; and

computing a distance between the pair of electrodes as a function of the computed ratio and the reference distance.

2. The method of claim 1, wherein the measured electrical parameter is a measured field potential of the generated electrical field.

3. The method of claim 1, wherein the measured electrical parameter is a measured impedance.

4. The method of claim 1, wherein the ratio is computed by dividing the measured electrical parameter by the measured reference electrical parameter.

5. The method of claim 1, further comprising determining the relative positioning between the two leads at least partially based on the computed distance.

6. The method of claim 5, wherein the relative positioning is the distance between the two leads.

7. The method of claim 5, wherein the relative positioning is the angle between the two leads.

8. The method of claim 5, further comprising activating a third one of another pair of electrodes respectively carried by the two leads to generate another electrical field within the tissue, repeating the electrical parameter measuring at a fourth one of the other pair of electrodes, repeating the reference electrical parameter measuring at another reference electrode, and repeating the ratio computing and distance computing steps to determine another distance between the other pair of electrodes.

9. The method of claim 8, further comprising:

plotting the distances; and

fitting a lead model to the plotted distances, wherein the relative positioning between the two leads is determined based on the fitted lead model.

10. The method of claim 1, wherein three leads are operated, the three leads including a middle lead and a pair of leads flanking the middle lead, the method further comprising identifying the middle lead based on the computed distance.

11. The method of claim 1, further comprising determining a longitudinal stagger between the two leads, and selecting the pair of electrodes having the least amount of longitudinal stagger based on the determined longitudinal stagger.

12. The method of claim 1, further comprising displaying the relative positioning of the two leads based on the computed distance.

13. The method of claim 1, further comprising programming a neurostimulator with a plurality of stimulation parameters based on the computed distance.

14. The method of claim 1, wherein the tissue is spinal cord tissue.

15. A medical system, comprising:

a first lead configured for being placed adjacent tissue of a patient, the first lead carrying a first electrode and a reference electrode;

a second lead configured for being placed adjacent the tissue of the patient, the second lead carrying a second electrode;

a controller configured for activating the first electrode to generate an electrical field within the tissue;

monitoring circuitry configured for measuring an electrical parameter in response to the generated electrical field at the second electrode, and measuring a reference electrical parameter in response to the generated electrical field at the reference electrode, wherein a reference distance between the first electrode and the reference electrode is known prior to generation of the electrical field; and

at least one processor configured for computing a ratio between the measured electrical parameter and the measured reference electrical parameter, and computing a distance between the first and second electrodes as a function of the computed ratio and the reference distance.

16. The medical system of claim 15, wherein the measured electrical parameter is a measured field potential of the generated electrical field.

17. The medical system of claim 15, wherein the measured electrical parameter is a measured impedance.

18. The medical system of claim 15, wherein the at least one processor is configured for computing ratio by dividing the measured electrical parameter by the measured reference electrical parameter.

19. The medical system of claim 15, wherein the at least one processor is configured for determining the relative positioning between the two leads at least partially based on the computed distance.

20. The medical system of claim 19, wherein the relative positioning is the distance between the two leads.

21. The medical system of claim 19, wherein the relative positioning is the angle between the two leads.

22. The medical system of claim 21, wherein the first lead carries a third electrode and another reference electrode, and the second lead carries a fourth electrode, wherein the controller is configured for activating the third electrode to generate another electrical field within the tissue, the monitoring circuitry is configured for repeating the electrical parameter measuring and the reference electrical parameter measuring with respect to the fourth electrode and the other reference electrode, and the at least one processor is configured for performing the ratio computing and distance computing to determine another distance between the third and fourth electrodes.

23. The medical system of claim 22, wherein the at least one processor is configured for plotting the first and second distances, fitting a straight line or a curve to the first and second plotted distances, and determining the relative positioning between the two leads based on the fitted straight line or curve.

24. The medical system of claim 15, further comprising a third lead configured for being placed adjacent tissue of a patient, wherein the first, second, and third leads are configured to be arranged as a middle lead and two leads flanking the middle leads, the at least one processor configured for identifying the middle lead based on the computed distance.

25. The medical system of claim 15, wherein the at least one processor is configured for determining a longitudinal stagger between the two leads, and selecting the first and second electrodes having the least amount of longitudinal stagger based on the determined longitudinal stagger.

26. The medical system of claim 15, further comprising a monitor configured for displaying the relative positioning of the two leads based on the computed distance.

27. The medical system of claim 15, further comprising a neurostimulator, wherein the at least one processor is configured for programming the neurostimulator with a plurality of stimulation parameters based on the computed distance.

28. The medical system of claim 15, further comprising an implantable device and an external device, wherein the implantable device contains the controller, and the external control device contains one or more of the at least one processor.