Porous Substrates for Implantation
First Claim
1. A method of forming a porous substrate for implantation into a human or animal body comprising the steps of:
- (i) forming a spacer which is adapted to define an open-cell pore network of the porous substrate by taking a model of the required porous structure, and creating a spacer representing the required porous structure using three-dimensional modelling;
(ii) infiltrating material to form a load-bearing scaffold structure of the substrate about the spacer; and
(iii) forming the load-bearing scaffold structure with an open cell pore network defined by the spacer.
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Abstract
A porous substrate or implant for implantation into a human or animal body constructed from a structural material and having one or more regions which when implanted are subjected to a relatively lower mechanical loading. The region(s) are constructed with lesser mechanical strength by having a lesser amount of structural material in said region(s) relative to other regions. This is achieved by controlling pore volume fraction in the regions. A spacer is adapted to define an open-cell pore network by taking a model of the required porous structure, and creating the spacer to represent the required porous structure using three-dimensional modelling. Material to form the substrate about the spacer in infiltrated the scaffold structure formed.
776 Citations
41 Claims
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1. A method of forming a porous substrate for implantation into a human or animal body comprising the steps of:
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(i) forming a spacer which is adapted to define an open-cell pore network of the porous substrate by taking a model of the required porous structure, and creating a spacer representing the required porous structure using three-dimensional modelling; (ii) infiltrating material to form a load-bearing scaffold structure of the substrate about the spacer; and (iii) forming the load-bearing scaffold structure with an open cell pore network defined by the spacer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A porous substrate for implantation into a human or animal body constructed by the method of forming a porous substrate comprising the steps of:
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forming a spacer which is adapted to define an open-cell pore network of the porous substrate by taking a model of the required porous structure, and creating a spacer representing the required porous structure using three-dimensional modelling; infiltrating material to form a load-bearing scaffold structure of the substrate about the spacer; and forming the load-bearing scaffold structure with an open cell pore network defined by the spacer. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 40, 41)
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- 38. A spacer for forming a porous substrate for implantation into a human or animal body the spacer being a three-dimensional array of spacer material for imparting a pore structure to structural material forming the substrate, the spacer having being formed by taking a model of the required porous structure, and creating the spacer representing the porous structure using three-dimensional modelling.
Specification