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HOMOGENEOUS DIFFERENTIATION OF HEPATOCYTE-LIKE CELLS FROM EMBRYONIC STEM CELLS

  • US 20100143313A1
  • Filed: 12/10/2009
  • Published: 06/10/2010
  • Est. Priority Date: 12/10/2008
  • Status: Abandoned Application
First Claim
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1. A method to differentiate pluripotent stem (PS) cells into mature functional hepatocytes, comprising:

  • (a) differentiating PS cells into monolayer colonies of early endodermal cell populations, and(b) maturating of the endodermal cell population into hepatic lineage cells expressing hepatocyte lineage markers and/or demonstrating hepatocyte function.

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